Functional independence, frailty and perceived quality of life in patients who developed delirium during ICU stay: a prospective cohort study

Table 2 Barthel Index and CFS scores

Survey	Time	No delirium	Delirium	p (*)	VD.A (**)
Barthel index, median, [IQR]	ICU discharge (T1)	70 [47, 5–100]	50 [30–65]	< 0.001	0.707^b
	Hospital discharge (T2)	90 [55–100]	55 [50–85]	< 0.001	0.713^a
	2 years after hospital discharge (T3)	100 [90–100]	85 [75–98, 8]	< 0.001	0.679^b
Clinical Frailty Scale, median, [IQR]	On ICU admission (T0)	3 [3–4]	3 [3–4]	0.361	0.457
Clinical Frailty Scale, median, [IQR]	Two years after hospital discharge (T3)	3 [3–4]	4 [3–4, 8]	< 0.001	0.307^b

IQR = interquartile range; VD.A = Vargha and Delaney’s A
(*) = Signs test sign test for related samples
(**) = Regarding size effect with VD.A
^aLarge effect (≥ 0.71 or ≤ 0.29)
^bModerate effect (0.64–0.71 < or > 0.29–0.34)
^cSmall effect (between 0.56–0.64 or 0.34–0.44). Values close to 1 or 0 indicate a strong intensity of the mean difference

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