Table 4 Comparison of the pathological findings of patients with micro- and macro- medullary thyroid carcinoma
Micro (n = 56) | Macro (n = 142) | p | |
|---|---|---|---|
Lobe (left/right) (n) | 28/28 | 72/70 | 0.929 |
Bilateral tumor (n) | 8 | 38 | 0.061 |
Multifocal tumor (n) | 10 | 42 | 0.091 |
Major tumor size (cm) | 0.8 ± 0.2 | 2.4 ± 1.2 | < 0.001 |
Total tumor size (cm) | 0.9 ± 0.4 | 2.8 ± 1.9 | < 0.001 |
Capsular invasion (n) | 12 | 45 | 0.151 |
Extrathyroidal invasion (n) | 4 | 18 | 0.265 |
Parathyroid gland dissection (n) | 19 | 47 | 0.911 |
No. of harvested central LN | 6 (3, 11) | 8 (4, 12) | 0.121 |
No. of positive central LN | 0 (0, 1) | 1 (0, 4) | < 0.001 |
No. of harvested lateral LN | 24 (15, 34) | 21 (16, 32) | 0.874 |
No. of positive lateral LN | 2 (0, 4) | 4 (1, 9) | 0.057 |
N staging (n) | 0.070 | ||
0 | 29 | 56 | |
1a | 11 | 20 | |
1b | 16 | 66 | |
TNM staging (n) | < 0.001 | ||
I | 28 | 28 | |
II | 1 | 23 | |
III | 10 | 18 | |
IV | 17 | 73 | |
TNM staging (n) | |||
I/II–IV | 28/28 | 28/114 | < 0.001 |