Validation of non-invasive indicators in the screening of metabolic dysfunction-associated fatty liver disease: a cross-sectional study among Uighurs in rural Xinjiang

Table 1 Basic demographic characteristics grouped by the presence of metabolic dysfunction-associated fatty liver disease

Variable	Overall	MAFLD		p
Variable	Overall	Yes	No	p
n	12,794	2118 (16.55)	10,676 (83.45)
Age (years)	38.10 ± 14.09	44.86 ± 12.06	36.76 ± 14.08	< 0.001
Sex				0.031
Men	6448 (50.40)	1022 (48.25)	5426 (50.82)
Women	6346 (49.60)	1096 (51.75)	5250 (49.18)
BMI (kg/m²)	25.77 ± 4.77	31.37 ± 5.00	25.04 ± 4.14	< 0.001
WC (cm)	90.88 ± 13.47	102.54 ± 12.70	88.56 ± 12.37	< 0.001
HC (cm)	100.83 ± 7.92	106.82 ± 8.70	99.64 ± 7.18	< 0.001
SBP (mm Hg)	128.91 ± 20.27	138.07 ± 22.23	127.09 ± 19.34	< 0.001
DBP (mm Hg)	75.21 ± 15.20	80.00 ± 13.46	74.26 ± 15.34	< 0.001
TG (mmol/L)	1.72 ± 1.46	2.39 ± 1.90	1.59 ± 1.32	< 0.001
TC (mmol/L)	4.75 ± 2.04	5.27 ± 2.20	4.65 ± 1.99	< 0.001
HDL-C (mmol/L)	1.57 ± 0.56	1.53 ± 0.60	1.57 ± 0.55	< 0.001
LDL-C (mmol/L)	2.65 ± 0.83	2.86 ± 1.02	2.61 ± 0.78	< 0.001
AST (U/L)	30.26 ± 24.14	36.86 ± 27.02	28.95 ± 23.31	< 0.001
ALT (U/L)	24.54 ± 13.35	25.72 ± 12.38	24.32 ± 13.52	< 0.001
GGT (U/L)	19.74 ± 17.33	26.36 ± 21.58	18.04 ± 15.61	< 0.001
FPG (mmol/L)	4.99 ± 2.04	5.62 ± 2.99	4.86 ± 1.77	< 0.001
T2DM	697 (5.4)	260 (12.3)	437 (4.1)	< 0.001
FLI	38.15 ± 28.27	68.94 ± 23.71	32.04 ± 24.92	< 0.001
HSI	35.58 ± 15.79	40.02 ± 15.21	34.70 ± 15.75	< 0.001
LAP	61.48 ± 65.60	109.09 ± 93.86	52.04 ± 53.58	< 0.001
VAI	2.02 ± 2.21	2.90 ± 2.85	1.85 ± 1.99	< 0.001
ZJU	36.94 ± 8.26	43.17 ± 8.36	35.71 ± 7.66	< 0.001

Values are presented as means ± standard or n (%)
MAFLD metabolic dysfunction-associated fatty liver disease, BMI body mass index, WC waist circumference, HC hip circumference, SBP systolic blood pressure, DBP diastolic blood pressure, TG triglycerides, TC total cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, AST aspartate aminotransferase, ALT alanine aminotransferase, GGT gamma-glutamyl transferase, FPG fasting plasma glucose, SCr serum creatinine, eGFR estimated glomerular filtration rate, T2DM type 2 diabetes mellitus, FLI fatty liver index, BMI body mass index, ZJU Zhejiang University Index, WC waist circumference, LAP lipid accumulation product, HSI hepatic steatosis index, VAI visceral adiposity index

ISSN: 2047-783X