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Table 2 Doses and characteristics of OAT received by women who were initiated on rapid titrations

From: Initiation and rapid titration of methadone and slow-release oral morphine (SROM) in an acute care, inpatient setting: a case series

 

Median (IQR)

N = 15 titrations (n, %)

Methadone (mg)

 Day 1

30 (30–42.5)

15 (100)

 Day 4

50 (42.5–60)

15 (100)

 Day 8

70 (65–75)

15 (100)

 Discharge dose

85 (70–92.5)

15 (100)

Slow-release oral morphine (mg)

 Day 1

110 (105–115)

2 (12.5)

 Day 4

130 (87.5–200)

8 (50)

 Day 8

260 (200–300)

8 (50)

 Discharge dose

340 (187.5–425)

8 (50)

Morphine Equivalents** (mg)

 Day 1

37.5 (31.25–133.75)

15 (100)

 Day 4

150 (46.5–367.5)

15 (100)

 Day 8

175 (90–332.5)

15 (100)

 Discharge dose

Not applicable

Not applicable

Hospital adverse events

 

0

Planned discharges

 

15/15

Patients seen in follow-up

 

9/12

Maintained OAT until delivery

 

5/11*(45)

  1. *Exclusion of incarcerated individual
  2. **Including n = 1 case prescribed PRN hydromorphone