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Table 1 Potential role of CASZ1 in tissue development

From: Role of the CASZ1 transcription factor in tissue development and disease

Tissue development

Cell types involved

Proposed mechanism

Refs.

Nerve

Dorsal root ganglia and spinal cord

Ratio between casz1a/casz1b isoforms

[45]

Retina

Retinal progenitor cells

Interacts with PRC or NuRD complex

[41,42,43]

Heart

Cardiomyocytes

Regulates cell cycle or interacts with CHD5/TBX20

[51,52,53]

Angiography

Endothelial cells

Regulates the Egfl7-RhoA pathway

[12, 59]