From: Role of the CASZ1 transcription factor in tissue development and disease
Tissue development | Cell types involved | Proposed mechanism | Refs. |
---|---|---|---|
Nerve | Dorsal root ganglia and spinal cord | Ratio between casz1a/casz1b isoforms | [45] |
Retina | Retinal progenitor cells | Interacts with PRC or NuRD complex | |
Heart | Cardiomyocytes | Regulates cell cycle or interacts with CHD5/TBX20 | |
Angiography | Endothelial cells | Regulates the Egfl7-RhoA pathway |