Table 1 Characteristics of the study subjects
Variables | Total (N = 41,842) | no-SRC (N = 36,084) | SRC (N = 5758) | F or χ2 | P value |
|---|---|---|---|---|---|
Male gender | 25,971 (62.1) | 21,784 (60.4) | 4187 (72.7) | 321.482 | < 0.001 |
Age(years) | 50.6 ± 14.8 | 49.7 ± 14.6 | 56.7 ± 14.7 | 1.896 | < 0.001 |
≥ 60 years | 10,531 (25.2) | 8338 (23.1) | 2193 (38.1) | 591.555 | < 0.001 |
Body mass index(kg/m2) | 22.6 ± 4.7 | 22.7 ± 4.7 | 22.6 ± 4.6 | 7.871 | 0.256 |
Systolic blood pressure (mmHg) | 125.9 ± 18.8 | 125.3 ± 18.6 | 130 ± 19.5 | 27.181 | < 0.001 |
Diastolic blood pressure(mmHg) | 76.8 ± 11.6 | 76.6 ± 11.6 | 78.5 ± 11.7 | 0.95 | < 0.001 |
Mean arterial pressure (mmHg) | 93.2 ± 13 | 92.8 ± 13 | 95.7 ± 13.1 | 1.00 | < 0.001 |
Hypertension | 10,720 (25.6) | 8827 (24.5) | 1893 (32.9) | 184.461 | < 0.001 |
HbA1c (%) | 6.0 ± 1.0 | 5.9 ± 0.9 | 6.1 ± 1.1 | 11.54 | < 0.001 |
Albumin(g/L) | 44.7 ± 2.5 | 44.8 ± 2.5 | 44.4 ± 2.5 | 0.105 | < 0.001 |
Fasting plasma glucose(mmol/L) | 5.4 ± 1.4 | 5.3 ± 1.4 | 5.6 ± 1.6 | 114.133 | < 0.001 |
Diabetes mellitus | 2953 (7.0) | 2359 (6.5) | 576 (10.0) | 91.455 | < 0.001 |
HDL-cholesterol (mmol/L) | 1.4 ± 0.3 | 1.4 ± 0.3 | 1.3 ± 0.3 | 0.055 | < 0.001 |
LDL- cholesterol (mmol/L) | 2.8 ± 0.7 | 2.8 ± 0.7 | 2.8 ± 0.7 | 2.202 | 0.524 |
Thyroid stimulating hormone (μIU/ml) | 2.4 ± 2.1 | 2.4 ± 2 | 2.3 ± 2.5 | 0.095 | 0.305 |
Free triiodothyronine (pmol/L) | 5.4 ± 0.7 | 5.4 ± 0.8 | 5.4 ± 0.7 | 1.975 | 0.105 |
Free thyroxine (pmol/L) | 10.7 ± 1.9 | 10.7 ± 1.9 | 10.7 ± 1.7 | 1.222 | 0.625 |
Triglyceride(mmol/L) | 1.68 ± 1.47 | 1.67 ± 1.48 | 1.74 ± 1.40 | 0.005 | 0.001 |
Total cholesterol (mmol/L) | 4.8 ± 0.9 | 4.8 ± 0.9 | 4.8 ± 0.9 | 1.395 | 0.162 |
Urea nitrogen (mmol/L) | 5.0 ± 1.4 | 5.0 ± 1.4 | 5.2 ± 1.5 | 18.938 | < 0.001 |
Serum creatinine(mg/dl) | 0.80 ± 0.25 | 0.80 ± 0.25 | 0.83 ± 0.22 | 0.003 | < 0.001 |
eGFR[ml min−1 (1.73m2)−1] | 99.1 ± 17.3 | 99.9 ± 17.2 | 94.0 ± 17.2 | 0.181 | < 0.001 |
< 60 | 1376 (3.3) | 1115 (3.1) | 261 (4.5) | ||
60– < 90 | 9143 (21.8) | 7377 (20.4) | 1766 (30.7) | ||
≥ 90 | 31,323 (74.9) | 27,592 (76.5) | 3731 (64.8) | ||
Uric acid(μmol/L) | 335.6 ± 87.9 | 334.4 ± 88.2 | 343.3 ± 85.9 | 6.474 | < 0.001 |