Association of elastic power in mechanical ventilation with the severity of acute respiratory distress syndrome: a retrospective study

Table 2 Univariate logistic regression analysis of risk factors for moderate-severe ARDS

Variables	OR (95% CI)	P value	Variables	OR (95% CI)	P value
Age (years)	0.98 (0.97–0.99)	0.005	Chronic renal	1.18 (0.38–3.71)	0.773
Gender (male)	1.00 (0.64–1.56)	0.985	Diabetes	0.95 (0.56–1.59)	0.836
BMI (kg/m²)	1.03 (1.00–1.07)	0.071	Respiratory mechanics parameters
PBW (kg)	1.00 (0.98–1.03)	0.653	VT (ml/kg PBW)	1.02 (0.89–1.17)	0.739
SOFA score	1.11 (1.04–1.18)	0.003	PEEP (cmH₂O)	1.31 (1.21–1.43)	< 0.001
SAPS II	1.00 (0.98–1.01)	0.790	Pplat (cmH₂O)	1.15 (1.1–1.21)	< 0.001
Causes of ARDS			ΔP (cmH₂O)	1.04 (0.99–1.10)	0.096
Sepsis	1.18 (0.74–1.89)	0.491	RR (bpm)	1.11 (1.06–1.17)	< 0.001
Respiratory disease	1.07 (0.67–1.72)	0.769	Cst (ml/cmH₂O)	0.99 (0.98–1.01)	0.445
Trauma	3.4 (0.78–14.9)	0.105	MP (J/min)	1.15 (1.11–1.20)	< 0.001
Others	0.62 (0.34–1.14)	0.125	EP (J/min)	1.21 (1.15–1.28)	< 0.001
Comorbidities			FiO₂ (%)	1.06 (1.04–1.08)	< 0.001
Coronary artery	0.66 (0.35–1.25)	0.205	Physiological variables in the first 24 h
COPD	1.48 (0.54–4.04)	0.446	PH	0.21 (0.03–1.64)	0.135
Chronic liver	0.54 (0.09–3.26)	0.500	PCO₂ (mmHg)	1.04 (1.02–1.06)	< 0.001

ARDS acute respiratory distresssyndrome, BMI body mass index, PBW predicted body weight, SOFA sequential organ failure assessment, SAPS II simplified acute physiology score II, COPD chronic obstructive pulmonary disease, PCO₂ partial pressure of carbon dioxide, VT tidal volume, PEEP positive end expiratory pressure, Pplat plateau pressure, ΔP driving pressure, RR respiratory rate, Cst static lung compliance, MP mechanical power, EP elastic power, FiO₂ inspired oxygen fraction

ISSN: 2047-783X