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Table 2 Biomarker levels

From: Utilizing neurodegenerative markers for the diagnostic evaluation of amyotrophic lateral sclerosis

 

Group

p

ALS

CG

Median

Min

Max

Median

Min

Max

Clusterin CSF [μg/l]

2148

843

15,646

1987.5

500

3460

0.038

Tau-protein CSF [ng/l]

323.5

29

923

177.5

55

574

 < 0.0001

Beta-amyloid1-42 CSF [ng/l]

920.5

283

1491

918

122

1308

0.774

p-tau protein CSF [ng/l]

43.85

16.40

107.1

29

17

66.3

0.001

  1. The table summarizes statistical comparisons among patients with ALS and a control group. We monitored biomarker levels—clusterin, tau protein, beta-amyloid 1–42, and p-Tau protein in cerebrospinal fluid. The values of significance for the Mann–Whitney U-test are provided in the last column, with tests conducted at a significance level of 0.05
  2. ALS, amyotrophic lateral sclerosis; CG, control group; CSF, cerebrospinal fluid