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Fig. 7 | European Journal of Medical Research

Fig. 7

From: Decidual stromal cells-derived exosomes incurred insufficient migration and invasion of trophoblast by disturbing of β-TrCP-mediated snail ubiquitination and degradation in unexplained recurrent spontaneous abortion

Fig. 7

Verify the interaction of β-TrCP and snail. A Immunocoprecipitation suggested that β-TrCP interacts with snail: the WB results of the input showed that the target protein was expressed in the HTR8/SVneo cells, and β-TrCP can precipitate snail, meanwhile, snail can precipitate β-TrCP. B Changes in the level of snail and β-TrCP on the cell surface after treatment with the proteasome inhibitor MG132 (blank, 0.125 μM, 0.25 μM, 0.5 μM, 1.0 μM).The results showed that with the increase of MG132 concentration, the expression of snail gradually increased in a concentration-dependent manner, while the expression of β- TrCP had no significant change. Full-length blots/gels are presented in Additional file 2 named WB-original picture

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European Journal of Medical Research

ISSN: 2047-783X

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