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Fig. 8 | European Journal of Medical Research

Fig. 8

From: Decidual stromal cells-derived exosomes incurred insufficient migration and invasion of trophoblast by disturbing of β-TrCP-mediated snail ubiquitination and degradation in unexplained recurrent spontaneous abortion

Fig. 8

Down-regulation of snail or overexpression of β-Trcp reversed the effects of DSC-exos on trophoblast cell. A-1 Representative western blot images showing the relative levels of β-Trcp, E-cadherin, N-cadherin, vimentin, and snail proteins in HTR8/SVneo treated with N-DSC-Exos + MG132 and URSA-DSC-exos + MG132. A2-4 Representative western blot images showing the relative levels of β-Trcp, E-cadherin, N-cadherin, vimentin, and snail proteins in HTR8/SVneo transfected with si-snail, si-β-TrCP or infected overexpression Lentivirus of β-TrCP. Fig. 4 Fluorescence photos of infection with lentivirus. B Wound-healing assays were performed using HTR8/SVneo cells

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