Table 2 Clinical characteristics of EWS patients
Variable | Unmatched | p-value | Propensity score (1:1)-matched | p-value | ||
|---|---|---|---|---|---|---|
Patients ≤ 40 (n = 4058) | Patients > 40 (n = 542) | Patients ≤ 40 (n = 542) | Patients > 40 (n = 542) | |||
AJCC analytic stage group (%) | ||||||
 1 | 422 (9.9) | 59 (10.1) | 0.128 | 61 (10.4) | 59 (10.1) | 0.255 |
 2 | 1144 (26.7) | 172 (29.5) | 163 (27.9) | 172 (29.5) | ||
 3 | 94 (2.2) | 18 (3.1) | 9 (1.5) | 18 (3.1) | ||
 4 | 1055 (24.6) | 151 (25.9) | 141 (24.1) | 151 (25.9) | ||
 Unknown | 1565 (36.6) | 184 (31.5) | 210 (36.0) | 184 (31.5) | ||
 Anaplastic (grade) | 634 (16.8) | 87 (17.4) | 0.728 | 82 (16.0) | 87 (17.4) | 0.546 |
Charlson-Deyo score, n (%) | ||||||
 0 | 3880 (95.6) | 458 (84.5) | < 0.001 | 558 (95.5) | 494 (84.6) | < 0.001 |
 1 | 147 (3.6) | 60 (11.1) | 23 (3.9) | 65 (11.1) | ||
 2 | 23 (0.6) | 18 (3.3) | 1 (0.2) | 18 (3.1) | ||
 ≥ 3 | 8 (0.2) | 6 (1.1) | 2 (0.3) | 7 (1.2) | ||
Primary site, n (%) | ||||||
 Long bones of upper limb (C400) | 453 (10.6) | 52 (8.9) |  < 0.001 | 68 (11.6) | 52 (8.9) |  < 0.001 |
 Short bones of upper limb (C401) | 44 (1.0) | 10 (1.7) | 10 (1.7) | 10 (1.7) | ||
 Long bones of lower limb (C402) | 1093 (25.5) | 132 (22.6) | 149 (25.5) | 109 (18.7) | ||
 Short bones of lower limb (C403) | 155 (3.6) | 14 (2.4) | 18 (3.1) | 14 (2.4) | ||
 Pelvic bones, sacrum, coccyx (C414) | 1032 (25.4) | 122 (22.5) | 152 (26.0) | 132 (22.6) | ||
 Bone of limb, NOS (C409) | 43 (1.0) | 10 (1.7) | 6 (1.0) | 10 (1.7) | ||
 Bones of skull and face (C410) | 201 (4.7) | 31 (5.3) | 17 (2.9) | 31 (5.3) | ||
 Mandible (C411) | 59 (1.4) | 9 (1.5) | 12 (2.1) | 9 (1.5) | ||
 Vertebral column (C412) | 422 (9.9) | 94 (16.1) | 52 (8.9) | 94 (16.1) | ||
 Rib, sternum, clavicle (C413) | 476 (11.1) | 60 (10.3) | 67 (11.5) | 60 (10.3) | ||
 Overlapping lesions (C408 + C418) | 47 (1.1) | 13 (2.0) | 6 (1.0) | 12 (2.0) | ||
 Bone of non-limb, NOS (419) | 195 (4.6) | 51 (8.7) | 27 (4.6) | 51 (8.7) | ||
 Appendicular tumor (C400-403, C409, C414) | 3075 (71.8) (app.) | 378 (64.7) (app.) | < 0.001 | 403 (68.9) (app.) | 327 (56.0) (app.) | < 0.001 |
 Axial tumor (C410, C411, C412, C419) | 877 (20.5) (axial) | 185 (31.7) (axial) | < 0.001 | 108 (18.5) (axial) | 185 (31.6) (axial) | < 0.001 |