Skip to main content

Table 1 The lack of characteristic genes and molecular markers and the unclear molecular mechanism makes the treatment and prognosis of Sarcopenia difficult

From: Epigenetic characterization of sarcopenia-associated genes based on machine learning and network screening

Research institute

Decreased muscle mass

Decreased muscle strength

Muscle hypofunction

EWGSOP

Less than healthy muscle mass

Adult #2 standard deviations

Muscle strength is lower than healthy

Adult #2 standard deviations

Pace lower than healthy

Adult #2 standard deviations

AWGS

Limb muscle mass/height 2:

    Male < 7.0 kg/m2

    Female < 5.4 kg/m2

Muscle strength:

    Male < 26 kg

    Female < 18 kg

Step speed < 0.8 m/s

IWGS

Extremity muscle mass/height2:

    Male ≤ 7.23 kg/m2

    Female ≤ 5.67 kg/m2

Step speed < 1 m/s

FNIH

Extremity muscle mass/height2/BMI*:

    Male < 0.789

    Female < 0.512

Muscle strength:

    Male < 26 kg

    Female < 16 kg

Step speed ≤ 0.8 m/s

  1. # Healthy adults: 19–39 years old; *BMI = body mass (kg)/height (m)2