Table 2 Targeted peptides commonly used in ischemic diseases
From: Current progression in application of extracellular vesicles in central nervous system diseases
Targeted peptides | Receptor cells | Targeted receptors | References |
|---|---|---|---|
RVG | Neuronal cells and endothelial cells | Nicotinic acetylcholine receptors | Lentz TL, J Mol Recognit, 1990 [79] |
cRGD | Ischemic endothelial cells | Integrin αvβ3 | Abumiya T, J Cereb Blood Flow Metab, 1999 [82] Li L, Exp Neurol, 2012 [83] Arosio D, Adv Drug Deliv Rev, 2015 [84] |
mAb–GAP43 | Ischemic neuronal cells | GAP43 | Liu W, J Nanobiotechnology, 2022 [86] |