Fig. 2

Mendelian randomization associations of inflammatory biomarker levels with intracranial aneurysm. Results were normalized applying the equation: beta = ln (odds ratio). Asterisk (*) indicated nominal significance of P < 0.05; MR Mendelian randomization, IA intracranial aneurysm, aSAH aneurysmal subarachnoid hemorrhage, uIA unruptured intracranial aneurysm, CTACK cutaneous T cell-attracting chemokine, NGF nerve growth factor, VEGF vascular endothelial growth factor, MIF macrophage migration inhibitory factor, TRAIL TNF-related apoptosis-inducing ligand, TNF tumor necrosis factor, SDF Stromal-derived factor, SCGF stem cell growth factor, SCF stem cell factor, IL interleukin, RANTES C–C chemokine ligand 5, PDGF-BB platelet-derived growth factor-BB, MIP macrophage inflammatory protein, Mig monokine induced by interferon-gamma, M-CSF monocyte colony-stimulating factor, MCP monocyte chemoattractant protein, IP interferon-gamma-inducible protein, HGF hepatocyte growth factor, GRO-alpha growth-regulated protein alpha, G-CSF granulocyte colony-stimulating factor, bFGF fibroblast growth factor basic