Table 1 Characteristics of all prognostic studies included in the meta-analysis
From: Prognostic, diagnostic and clinicopathological roles of tsRNAs: a meta-analysis in breast cancer
No | Study/TsRNA | Year | Country | Expression | Cut-off | Sample size | Data source | Detected sample | Follow-up time | Survival outcome | Survival analysis | Variables | Refc | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
HRa | 95% CIb | p-value | Obtained | |||||||||||||
1 | Sun, tRF-30-JZOYJE22RR33 | 2018 | China | Up | ΔCT | 52 | Clinical | Tissue | 30 | PFSd | Multei | 2.754 | 1.038–5.219 | 0.04 | Direct | 30153663 |
2 | Sun, tRF-27-ZDXPHO53KSN | 2018 | China | Up | ΔCT | 52 | Clinical | Tissue | 30 | PFS | Multi | 2.265 | 1.187–6.756 | 0.019 | Direct | 30153663 |
3 | Feng, tDR-000620 | 2018 | China | Down | Medf | 44 | Clinical | Plasma | 40 | RFSg | Multi | 0.265 | 0.073–0.959 | 0.043 | Direct | 30239174 |
4 | Shan, tRFdb-5024a | 2020 | China | Down | NA | 1081 | Database | Tissue | 250 | OSh | Unii | 0.52 | 0.37–0.74 |  < 0.001 | Direct | 32785169 |
5 | Shan, 5P_tRNA-Leu-CAA-4–1 | 2020 | China | Down | NA | 1081 | Database | Tissue | 250 | OS | Uni | 0.55 | 0.35–0.87 | 0.011 | Direct | 32785169 |
6 | Shan, ts-49 | 2020 | China | Down | NA | 1081 | Database | Tissue | 250 | OS | Uni | 0.4 | 0.17–0.93 | 0.032 | Direct | 32785169 |
7 | Shan, ts-34 | 2020 | China | Up | NA | 1081 | Database | Tissue | 250 | OS | Uni | 1.62 | 1.08–2.44 | 0.019 | Direct | 32785169 |
8 | Shan, ts-58 | 2020 | China | Up | NA | 1081 | Database | Tissue | 250 | OS | Uni | 1.56 | 1.1–2.2 | 0.013 | Direct | 32785169 |
9 | Wang, tRF-Glu-CTC-003 | 2020 | China | Down | NA | 144 | Clinical | Plasma | 60 | DFSj | Uni | 0.37 | 0.04–3.57 | 0.144 | KMk | 32,814,252 |
10 | Wang, tRF-Glu-CTC-003 | 2020 | China | Down | NA | 144 | Clinical | Plasma | 60 | OS | Uni | 0.9 | 0.1–8.29 | 0.1714 | KM | 32814252 |
11 | Wang, tRF-Arg-CCT-017 | 2021 | China | Up | Med | 120 | Clinical | Plasma | 60 | DFS | Uni | 2.23 | 0.03–193.98 | 0.0123 | KM | 33402674 |
12 | Wang, tRF-Arg-CCT-017 | 2021 | China | Up | Med | 120 | Clinical | Plasma | 60 | OS | Uni | 1.71 | 0.05–64.25 | 0.0428 | KM | 33402674 |
13 | Zhang, tRNA-Lys-TTT-3–1 | 2022 | China | Up | Med | 1101 | Database | Tissue | 260 | OS | Uni | 1.48 | 1.24–1.76 | 0.028 | KM | 35030975 |
14 | Zhang, tRNA-Gly-GCC-1–4 | 2022 | China | Up | Med | 1101 | Database | Tissue | 260 | OS | Uni | 1.64 | 1.37–1.95 | 0.043 | KM | 35030975 |
15 | Zhang, tRNA- Ser-AGA-2–5 | 2022 | China | Up | Med | 1101 | Database | Tissue | 260 | OS | Uni | 2.24 | 1.83–2.74 | 0.0041 | KM | 35030975 |
16 | Zhang, tRNA-Ser-AGA-3–1 | 2022 | China | Up | Med | 1101 | Database | Tissue | 260 | OS | Uni | 1.39 | 1.15–1.68 | 0.021 | KM | 35030975 |
17 | Zhang, tRNA-His-GTG-1–1 | 2022 | China | Down | Med | 1101 | Database | Tissue | 260 | OS | Uni | 0.63 | 0.52–0.76 | 0.041 | KM | 35030975 |
18 | Liu, 5'-tRF-Cys | 2022 | USA | Up | NA | 978 | Database | Tissue | 120 | OS | Multi | 1.6 | 1.02–2.52 | 0.041 | Direct | 35654044 |
19 | Liu, 5'-tRF-Cys | 2022 | USA | Up | NA | 671 | Database | Tissue | 120 | OS | Multi | 1.76 | 1.02–3.04 | 0.04 | Direct | 35654044 |
20 | Liu, 5'-tRF-Cys | 2022 | USA | Up | NA | 1066 | Database | Tissue | 120 | OS | Uni | 1.57 | 1.23–2.02 | 0.011 | KM | 35654044 |