Table 1 Baselines mean clinical, laboratory, and echocardiographic characteristics
From: Optimizing cardiac amyloidosis assessment: utility of 1-h and 3-h 99mTc-PYP imaging
Category | Overall cohort (n = 27) | Negative group (n = 13) | Positive group (n = 14) | p |
|---|---|---|---|---|
Clinical | ||||
Age (yrs) | 75 ± 11 | 71.3 ± 13.6 | 79.2 ± 6.1 | 0.05 |
Male sex (%) | 21 (77.8%) | 8 (61.5%) | 13 (92.9%) | 0.07 |
BMI, kg/m2 | 22.9 (15.9 – 34.8) | 22.7 (15.9–34.9) | 23 (19.5–26.5) | 0.816 |
NYHA class III, IV | 17 (63%) | 7 (53.83%) | 10 (71.4%) | 0.44 |
History of angina | 8 (29.6%) | 3 (23.1%) | 5 (35.7%) | 0.678 |
Present angina | 2 (7.4%) | 2 (15.4%) | – | 0.222 |
Coronary artery disease | 5 (18.5%) | 2 (15.4%) | 3 (21.4%) | 1.0 |
Hypertension | 20 (74.1%) | 9 (69.2%) | 11 (78.6%) | 0.678 |
Hyperlipidemia | 7 (25.9%) | 2 (15.4%) | 5 (35.7%) | 0.385 |
Laboratory | ||||
Troponin T (ng/mL) | 0.070 (0.016–0.153) | 0.031 (0.016–0.098) | 0.094 (0.034–0.153) | 0.06 |
Creatinine (mg/dL) | 1.2 ± 0.7 | 1.3 ± 1 | 1.2 ± 0.3 | 0.590 |
Calcium (mg/dL) | 9.12 ± 0.57 | 9.08 ± 0.39 | 9.16 ± 0.75 | 0.754 |
NT-proBNP (pg/mL) | 7131 (182–25,909) | 4689 (182–25,909) | 9573 (577–17,307) | 0.219 |
GFR (mL/min) | 46.2 ± 15.4 | 48.3 ± 21.4 | 46.1 ± 10.4 | 0.308 |
Echocardiographic | ||||
EF (%) | 44.3 ± 15.6 | 47.6 ± 16.4 | 41.2 ± 14.6 | 0.298 |
EDV (mL) | 97.36 ± 38.2 | 112 ± 45.3 | 83.2 ± 26.2 | 0.056 |
ESV (mL) | 50.3 ± 27.2 | 54.7 ± 36.2 | 41.2 ± 20 | 0.207 |
LA volume (mL) | 91.87 ± 38.1 | 104.1 ± 47.6 | 78.4 ± 17.9 | 0.108 |
Interventricular septum thickness (mm) | 15.2 ± 2.7 | 14.1 ± 2.3 | 16.2 ± 2.8 | 0.044 |
LV posterior wall thickness (mm) | 14.1 ± 3 | 13.1 ± 2.1 | 15.1 ± 3.6 | 0.105 |