Table 2 GFAP suppressors

Prosaptide

A peptide derived from a 14-amino-acid neurotrophic sequence of human glycoprotein prosaposin

Precise site of action is unknown (Down-regulation of GFAP expression)

[23, 25]

WF-A

A steroidal lactone isolated from Ayurvedic medicine (Winter cherry)

Covalent modification of the single Cys-294 of GFAP(Inhibit GFAP and the related IF)

[26, 27]

Ibudilast (AV411)

A board-spectrum PDE inhibitor

Precise site of action is unknown (Inhibit methamphetamine-induced GFAP upregulatio))

[28]

aspirin/acetylsalicylic acid

Cox-2 inhibitor

Precise site of action is unknown (Down-regulation of GFAP expression)

[29]

clomipramine

Tricyclic antidepressant

Precise site of action is unknown (Down-regulation of GFAP expression)

[30]

curcumin

Extracted from turmeric

Precise site of action is unknown (Down-regulation of GFAP expression)

[31]