Fig. 2From: Gentiopicroside inhibits the progression of gastric cancer through modulating EGFR/PI3K/AKT signaling pathwayGPS promoted the cellular apoptosis, which was related to the rupture of mitochondrial integrity. A GPS induced cellular apoptosis in AGS and HGC27 cells. B TEM showed that GPS induced rupture of mitochondrial structure. C GPS induced decrease of JC-1 aggregate and increase of JC-1 monomer in cells. D GPS regulated the expression of apoptosis-related proteins (*P < 0.05, **P < 0.01, ***P < 0.001)Back to article page