Fig. 6

GPS promoted GC cells apoptosis by inhibiting the EGFR/PI3K/AKT axis. A The tendency of GPS (100 μM)-induced decrease in JC-1 aggregates and increase in JC-1 monomers in GC cells could be reversed after co-application of overexpressing EGFR plasmid. B The tendency of GPS (100 μM) to promote apoptosis in GC cells could be reversed after co-application of overexpressing EGFR plasmids. (***P < 0.001; ns, non-significant)