Table 3 The PANTHER classification system of hub genes
Gene | Gene name | Gene ID | PANTHER Family/Subfamily | PANTHER protein class |
|---|---|---|---|---|
VNN1 | Pantetheinase | HUMAN|HGNC = 12,705|UniProtKB = O95497 | PANTETHEINASE (PTHR10609:SF16) | Hydrolase |
SERPINB2 | Plasminogen activator inhibitor 2 | HUMAN|HGNC = 8584|UniProtKB = P05120 | PLASMINOGEN ACTIVATOR INHIBITOR 2 (PTHR11461:SF61) | Protease inhibitor |
ETFDH | Electron transfer flavoprotein–ubiquinone oxidoreductase, mitochondrial | HUMAN|HGNC = 3483|UniProtKB = Q16134 | ELECTRON TRANSFER FLAVOPROTEIN-UBIQUINONE OXIDOREDUCTASE, MITOCHONDRIAL (PTHR10617:SF107) | Oxidoreductase |
FLT3LG | Fms-related tyrosine kinase 3 ligand | HUMAN|HGNC = 3766|UniProtKB = P49771 | FMS-RELATED TYROSINE KINASE 3 LIGAND (PTHR11032:SF1) | Cytokine |
DYRK1A | Dual specificity tyrosine–phosphorylation-regulated kinase 1A | HUMAN|HGNC = 3091|UniProtKB = Q13627 | DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 1A (PTHR24058:SF121) | Protein modifying enzyme |
DCN | Decorin | HUMAN|HGNC = 2705|UniProtKB = P07585 | DECORIN (PTHR45712:SF14) | – |
FKBP8 | Peptidyl-prolyl cis–trans isomerase FKBP8 | HUMAN|HGNC = 3724|UniProtKB = Q14318 | PEPTIDYL-PROLYL CIS–TRANS ISOMERASE FKBP8 (PTHR46512:SF3) | Chaperone |