Identification of potential crucial genes and therapeutic targets for epilepsy

Table 1 Epilepsy risk SNPs regulate GADD45A and PTPRO expression in human brain tissue

SNP	Target gene	eQTL-p	Human brain tissue
Rs4794333	GADD45A	0.0037	Thalamus
Rs68082256	GADD45A	0.022	Medulla
Rs11943905	GADD45A	0.045	Temporal cortex
Rs12185644	GADD45A	0.041	Temporal cortex
Rs6432877	PTPRO	0.035	Occipital cortex
Rs2212656	PTPRO	0.031	Occipital cortex
Rs1402398	PTPRO	0.042	Putamen
Rs11890028	PTPRO	0.016	Frontal cortex
Rs887696	PTPRO	0.036	Occipital cortex
Rs1044352	PTPRO	0.0052	Occipital cortex
Rs13200150	PTPRO	0.037	Temporal cortex
Rs4671319	PTPRO	0.036	Temporal cortex

ISSN: 2047-783X