Table 2 115 genes encoding proteins targeted by approved antiepileptic drugs

Phenobarbital, Primidone, Phenytoin, Carbamazepine, Valproate, Clonazepam, Clobazam, Gabapentin, Lamotrigine, Topiramate, Oxcarbazepine, Tiagabine, Levetiracetam, Zonisamide, Felbamate, Pregabalin, Vigabatrin

NR1I2, GRIA2, GABRA1, CHRNA4, CHRNA7, GRIK2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, GRIN3A, GRIN3B, GABRA3, GABRA6, GABRA5, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, SCN5A, SCN3A, CACNA1C, CACNA1D, CACNA1F, CACNA1S, CACNB1, CACNB2, CACNB3, CACNB4, CACNA1A, SCN8A, KCNH2, SCN1A, SCN1B, SCN2A, SCN4A, SCN7A, SCN9A, SCN10A, SCN11A, ALDH5A1, HDAC2, PPARA, PPARD, OGDH, SCN2B, SCN3B, SCN4B, PPARG, HDAC9, ACADSB, TSPO, CACNA2D1, KCNQ5, ADORA1, CACNA1B, CACNA2D2, KCNQ3, HTR3A, CACNA1E, ADRA2A, HRH1, OPRK1, ADORA2A, ADRA1A, DRD2, GABRA4, ADRB1, DRD1, DRD5, GABRA2, GABRB1, CHRM1, CHRM2, CHRM3,CHRM4, CHRM5, HTR2A, CA2, GRIK1, GRIK3, GRIK4, GRIK5, CA3, CA4, SLC6A1, SV2A, CA5B, CA10, CA11, CA12, CA13, MAOB, CA7, CA9, CACNA1H, CA1, CACNA1G, CA5A, CA6, CA8, CA14, CACNA1I, MAOA, ABAT, GABBR1, GSK3A, GABBR2, SLC5A6