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TableĀ 2 The MR-Egger intercept, MR-PRESSO, and heterogeneity tests for the causal relationship between lung function and frailty

From: Lung function and the risk of frailty in the European population: a mendelian randomization study

Exposure

Method

Frailty (outcome)

Beta

P

Cochran Q

MR-Egger intercept (P)

FEV1

MR-PRESSO Raw

āˆ’0.08

3.11Eāˆ’05

370.72

0.354

MR-PRESSO Outlier-corrected

āˆ’0.07

7.70Eāˆ’05

FEV1/FVC

MR-PRESSO Raw

āˆ’0.06

1.43Eāˆ’05

394.62

0.883

MR-PRESSO Outlier-corrected

āˆ’0.06

9.24Eāˆ’06

FVC

MR-PRESSO Raw

āˆ’0.01

0.682

347.28

0.602

MR-PRESSO Outlier-corrected

āˆ’0.00

0.865

PEF

MR-PRESSO Raw

āˆ’0.07

5.40Eāˆ’04

284.76

0.056

MR-PRESSO Outlier-corrected

āˆ’0.07

1.48Eāˆ’04

  1. FEV1 forced expiratory volume in the first second, FVC forced vital capacity, PEF peak expiratory flow, MR-PRESSO MR-Pleiotropy RESidual Sum and Outlier, N number, P P-value