Fig. 1

Filtering of high-throughput sequencing data of circRNAs in peripheral blood. Raw data from sequencing included reads that were of low quality, had contaminated joints, and/or had high levels of unknown base N. The statistics of filtering components of each of the two groups of original data are shown. N: the number of reads with an unknown base content greater than 5% and their proportion with respect to the total number of raw reads. Adapter: the number of reads containing the connector (contaminated reads from the connector) and their proportion with respect to the total number of raw reads. Low qual: the number and proportion of low-quality reads (reads with a mass value of less than 15 that account for more than 20% of the total base of the reads). Clean reads: the number of filtered reads and their proportion with respect to the total number of raw reads. A Statistical chart of components filtered from the raw data of the healthy control group. B Statistical chart of components filtered from the raw data of the AMI group. C Distribution map of base content in clean reads. D Base mass distribution of clean reads