Fig. 8

TMB and sensitivity to targeted drugs analysis of high- and low-risk groups. A Genes with the top 20 mutation frequencies in the high-risk group. B Genes with the top 20 mutation frequencies in the low-risk group. C Boxplot of TMB and risk group correlations. D The relationship between TMB and Kaplan–Meier survival. E Kaplan–Meier survival with TMB status and risk level. Differences in drug sensitivity across risk groups for F Alpelisib, G Ipatasertib, H Lapatinib, I Selumetinib, J Pictilisib, and K AZD4547