Table 4 GRADE assessment of the biomarkers
Quality assessment | Quality | ||||||
|---|---|---|---|---|---|---|---|
No of studies | Design | Risk of bias | Inconsistency | Indirectness | Imprecision | Other considerations | |
NGAL | |||||||
14 | Observational studies | Serious | No serious inconsistency | No serious indirectness | No serious imprecision | Reporting bias very strong association | ⊕⊕〇〇 low |
Cystatin-C | |||||||
10 | Observational studies | Serious | No serious inconsistency | No serious indirectness | No serious imprecision | Very strong association | ⊕⊕⊕〇 moderate |
uKIM-1 | |||||||
9 | Observational studies | Serious | No serious inconsistency | No serious indirectness | No serious imprecision | Reporting bias very strong association | ⊕⊕〇〇 low |
BNP | |||||||
12 | Observational studies | No serious risk of bias | No serious inconsistency | No serious indirectness | No serious imprecision | Very strong association | ⊕⊕⊕⊕ high |
GGT | |||||||
4 | Observational studies | No serious risk of bias | No serious inconsistency | No serious indirectness | No serious imprecision | Strong association | ⊕⊕⊕〇 moderate |
Albumin | |||||||
5 | Observational studies | No serious risk of bias | No serious inconsistency | No serious indirectness | No serious imprecision | Reporting bias strong association | ⊕⊕〇〇 low |
V/CR | |||||||
6 | Observational studies | Serious | No serious inconsistency | No serious indirectness | No serious imprecision | Reporting bias strong association | ⊕〇〇〇 very low |
Preprocedural hyperglycemia over 200 | |||||||
7 | Observational studies | Serious | Serious | No serious indirectness | No serious imprecision | Strong association | ⊕〇〇〇 very low |
Preprocedural hyperglycemia over 140 | |||||||
4 | Observational studies | Serious | Serious | No serious indirectness | No serious imprecision | None | ⊕〇〇〇 very low |
RDW | |||||||
5 | Observational studies | No serious risk of bias | No serious inconsistency | No serious indirectness | No serious imprecision | None | ⊕⊕〇〇 low |
Uric acid | |||||||
18 | Observational studies | No serious risk of bias | No serious inconsistency | No serious indirectness | No serious imprecision | Reporting bias | ⊕〇〇〇 very low |
PLR | |||||||
4 | Observational studies | No serious risk of bias | No serious inconsistency | No serious indirectness | No serious imprecision | None | ⊕⊕〇〇 low |
NLR | |||||||
5 | Observational studies | No serious risk of bias | No serious inconsistency | No serious indirectness | No serious imprecision | None | ⊕⊕〇〇 low |
HS-CRP | |||||||
9 | Observational studies | No serious risk of bias | No serious inconsistency | No serious indirectness | No serious imprecision | Reporting bias | ⊕〇〇〇 very low |
CRP | |||||||
5 | Observational studies | No serious risk of bias | No serious inconsistency | No serious indirectness | No serious imprecision | None | ⊕⊕〇〇 low |
BUN | |||||||
3 | Observational studies | No serious risk of bias | No serious inconsistency | No serious indirectness | No serious imprecision | None | ⊕⊕〇〇 low |
HCT | |||||||
8 | Observational studies | No serious risk of bias | No serious inconsistency | No serious indirectness | No serious imprecision | None | ⊕⊕〇〇 low |