Table 2 Receiver operating curve analysis of serum COMP and ADAMTS7 levels discriminating between patients with IVDD (Pfirrmann Grade III–V) and healthy subjects (Pfirrmann Grade I-II)
From: Diagnostic value of serum COMP and ADAMTS7 for intervertebral disc degeneration
Biomarker(ng/ml) | AUC | Cut-off value | Sensitivity | Specificity | Asymptotic 95% CI | |
|---|---|---|---|---|---|---|
Lower bound | Upper bound | |||||
COMP | 0.834 | 1021.05 | 0.714 | 0.857 | 0.747 | 0.922 |
ADAMTS7 | 0.889 | 102.47 | 0.841 | 0.857 | 0.813 | 0.964 |
Predicted probability | 0.931 | Â | Â | Â | 0.874 | 0.989 |