Table 3 The association between high expression of PIAS family genes and over survival of pan-cancer in different databases
Gene | role | Kaplan–Meier plotter OS | TCGA OS | TCGA + GTEx OS | PrognoScan OS |
|---|---|---|---|---|---|
PIAS1 | Protective | KIRC | KIRC, SKCM | KIRC | Â |
Detrimental | ESCA, LIHC, STAD, UCEC | ACC, KICH, LGG, LIHC | ACC, BRCA, COAD, KICH, LGG | Â | |
PIAS2 | Protective | KIRP, LUAD, OV, PAAD | COAD, KIRC | CHOL, KIRC | Brain cancer, |
Detrimental | LIHC, THCA | ACC, BLCA, LGG, LIHC, MESO, THCA | Â | Lung cancer, skin cancer | |
PIAS3 | Protective | KIRC, LUSC, THCA | Â | LUSC | Â |
Detrimental | BLCA, KIRP, LIHC, SARC, PAAD, STAD, THYM | ACC, KICH, KIRP, LAML, LGG, LIHC, MESO | ACC, KIRP, LGG, MESO | Colorectal cancer | |
PIAS4 | Protective | CESC, HNSC, PAAD, STAD, THYM, UCEC | HNSC, KIRC, UCEC | HNSC, KIRC | Lung cancer |
Detrimental | KIRP, PCPG, LIHC | ACC, LAML, LGG, MESO | MESO | Brain cancer |