Clinicopathological and molecular genetic alterations in monomorphic–epitheliotropic intestinal T-cell lymphoma of the small intestine

Table 2 Molecular genetic changes of MEITL in small intestine in 3 cases

Case	EBER	TCR gene rearrangement	NGS
Case	EBER	TCR gene rearrangement	Gene	Mutant Type	Mutant amino acid changes	Mutant abundance (%)
1	–	TCR⁃γ	JAK3	Missense	p.A573V	17.3
			SETD2	Frameshift indel	p.D2004I	13.2
			TP53	Missense	p.R248Q	24.7
			BCRO	Frameshift indel	p.L1262	6.5
2	–	TCR⁃β	JAK3	Missense	p.V674A	22.1
			SETD2	Missense	p.S1769T	9.4
			STAT5B	Missense	p.Y655F	6.9
			TP53	Frameshift indel	p.I232S	16.3
3	–	TCR⁃γ	JAK3	Missense	p.A573V	36.7
3	–	TCR⁃γ	STAT5B	Missense	p.N642H	11.8

ISSN: 2047-783X