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Table 1 Comparison of participants' baseline information

From: Threshold-modifying effect of the systemic inflammatory response index on kidney function decline in hypertensive patients

Features

eGFR > 60 mL/minute/1.73 m2 (N = 4490)

eGFR ≤ 60 mL/minute/1.73 m2 (N = 956)

P value

ACR < 30 mg/g (N = 4328)

ACR ≥ 30 mg/g (N = 1118)

P value

Age (years)

59.00 (47.00, 68.00)

72.00 (63.00, 80.00)

 < 0.001

60.00 (48.00, 70.00)

66.00 (55.00, 76.00)

 < 0.001

Gender (%)

  

0.001

  

0.301

Men

2288 (50.96%)

433 (45.29%)

 

2147 (49.61%)

574 (51.34%)

 

Women

2202 (49.04%)

523 (54.71%)

 

2181 (50.39%)

544 (48.66%)

 

BMI (kg/m2)

29.60 (25.90, 34.60)

29.30 (25.70, 34.00)

0.200

29.50 (25.90, 34.40)

30.10 (25.80, 35.30)

0.124

Diabetes (%)

  

 < 0.001

  

 < 0.001

No

3359 (74.81%)

566 (59.21%)

 

3342 (77.22%)

583 (52.15%)

 

Yes

1131 (25.19%)

390 (40.79%)

 

986 (22.78%)

535 (47.85%)

 

Smoking status (%)

  

 < 0.001

  

0.093

Never

2312 (51.49%)

467 (48.85%)

 

2241 (51.78%)

538 (48.12%)

 

Smoking former

1269 (28.26%)

338 (35.36%)

 

1257 (29.04%)

350 (31.31%)

 

Smoking now

909 (20.24%)

151 (15.79%)

 

830 (19.18%)

230 (20.57%)

 

Drinking status (%)

  

 < 0.001

  

0.046

Rarely drinker

714 (15.90%)

190 (19.87%)

 

708 (16.36%)

196 (17.53%)

 

Light drinker

621 (13.83%)

164 (17.15%)

 

602 (13.91%)

183 (16.37%)

 

Excessive drinker

3155 (70.27%)

602 (62.97%)

 

3018 (69.73%)

739 (66.10%)

 

Race/Ethnicity (%)

  

 < 0.001

  

0.013

Mexican American

567 (12.63%)

71 (7.43%)

 

482 (11.14%)

156 (13.95%)

 

Other Hispanic

498 (11.09%)

56 (5.86%)

 

446 (10.30%)

108 (9.66%)

 

Non-Hispanic White

1708 (38.04%)

405 (42.36%)

 

1717 (39.67%)

396 (35.42%)

 

Non-Hispanic Black

1121 (24.97%)

341 (35.67%)

 

1140 (26.34%)

322 (28.80%)

 

Other Race

596 (13.27%)

83 (8.68%)

 

543 (12.55%)

136 (12.16%)

 

Education (%)

  

 < 0.001

  

 < 0.001

Less than high school

1120 (24.94%)

297 (31.07%)

 

1044 (24.12%)

373 (33.36%)

 

High school

1069 (23.81%)

225 (23.54%)

 

1029 (23.78%)

265 (23.70%)

 

More than high school

2301 (51.25%)

434 (45.40%)

 

2255 (52.10%)

480 (42.93%)

 

Marital status (%)

  

 < 0.001

  

 < 0.001

Never married

563 (12.54%)

87 (9.10%)

 

540 (12.48%)

110 (9.84%)

 

Widowed/divorced/separated

1284 (28.60%)

412 (43.10%)

 

1271 (29.37%)

425 (38.01%)

 

Married/livingwith partner

2643 (58.86%)

457 (47.80%)

 

2517 (58.16%)

583 (52.15%)

 

WBC(× 109/L)

7.00 (5.80, 8.50)

7.00 (5.80, 8.40)

0.475

6.90 (5.70, 8.40)

7.30 (6.10, 8.80)

 < 0.001

Neutrophil (× 109/L)

4.00 (3.20, 5.20)

4.10 (3.30, 5.20)

0.540

4.00 (3.10, 5.10)

4.40 (3.40, 5.60)

 < 0.001

Lymphocyte(× 109/L)

2.00 (1.60, 2.50)

1.90 (1.50, 2.40)

 < 0.001

2.00 (1.60, 2.50)

1.90 (1.50, 2.50)

 < 0.001

Monocyte (× 109/L)

0.60 (0.40, 0.70)

0.60 (0.50, 0.70)

0.003

0.55 (0.40, 0.70)

0.60 (0.50, 0.70)

 < 0.001

PLT(× 109/L)

230.00 (195.00, 271.00)

215.00 (179.00, 257.00)

 < 0.001

228.00 (193.00, 270.00)

221.00 (186.00, 268.00)

0.004

Hb(g/dL)

14.00 (13.10, 15.00)

13.10 (12.00, 14.10)

 < 0.001

13.90 (12.90, 15.00)

13.60 (12.40, 14.67)

 < 0.001

ALT (IU/L)

22.00 (17.00, 29.00)

18.00 (14.00, 24.00)

 < 0.001

21.00 (17.00, 29.00)

20.00 (15.00, 27.00)

 < 0.001

AST (IU/L)

24.00 (20.00, 29.00)

23.00 (20.00, 27.00)

0.004

23.00 (20.00, 28.00)

23.00 (19.00, 29.00)

0.338

HDL-C (mmol/L)

1.29 (1.06, 1.58)

1.27 (1.03, 1.58)

0.247

1.29 (1.09, 1.58)

1.25 (1.01, 1.55)

 < 0.001

TG (mmol/L)

1.50 (0.99, 2.30)

1.57 (1.06, 2.29)

0.147

1.49 (0.99, 2.26)

1.61 (1.06, 2.47)

 < 0.001

TC (mmol/L)

4.96 (4.21, 5.71)

4.66 (3.90, 5.44)

 < 0.001

4.91 (4.19, 5.69)

4.81 (4.03, 5.66)

0.014

ALB (g/L)

43.00 (40.00, 45.00)

41.00 (39.00, 44.00)

 < 0.001

42.00 (40.00, 45.00)

42.00 (39.00, 44.00)

 < 0.001

Glucose (mmol/L)

5.44 (4.94, 6.33)

5.72 (5.05, 7.05)

 < 0.001

5.44 (4.94, 6.22)

5.94 (5.16, 8.26)

 < 0.001

HbA1c (%)

5.70 (5.40, 6.20)

6.00 (5.60, 6.70)

 < 0.001

5.70 (5.40, 6.10)

6.10 (5.60, 7.20)

 < 0.001

SIRI

1.09 (0.73, 1.62)

1.26 (0.81, 1.88)

 < 0.001

1.08 (0.72, 1.60)

1.30 (0.85, 1.98)

 < 0.001

  1. All continuous numeric variables are expressed using medians (quartiles) and categorical variables are quantified as numbers (percentages)
  2. PLT platelets, ALT alanine transaminase, AST aspartate transaminase, HDL-C high-density lipoprotein-cholesterol, TG triglycerides, TC total cholesterol, ALB Albumin, HbA1c glycosylated hemoglobin, SIRI Systemic Inflammation Response Index
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European Journal of Medical Research

ISSN: 2047-783X

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