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Fig. 7 | European Journal of Medical Research

Fig. 7

From: Multi-omics and immunogenomics analysis revealed PFKFB3 as a targetable hallmark and mediates sunitinib resistance in papillary renal cell carcinoma: in silico study with laboratory verification

Fig. 7

The association with clinical relevance and Immune infiltration of key GIRPI component gene PFKFB3. A Clone formation capability of ACHN cells exposed to different concentrations of 2-DG. B qRT-PCR analysis to verify the expression level of five GIRPI genes in RCC cell lines. C Kaplan–Meier survival of PFKFB3 in pRCC patients (OS, DSS, PFI). D The time-dependent ROC curves of PFKFB3. E PPI network of PFKFB3-related genes using STRING database. F GSVA analysis of potential mechanism involved in PFKFB3. G The underlying association between PFKFB3 and immune infiltration of cells. H The association between some immune microenvironment molecules and PFKFB3

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