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Fig. 9 | European Journal of Medical Research

Fig. 9

From: Functional analysis and validation of oncodrive gene AP3S1 in ovarian cancer through filtering of mutation data from whole-exome sequencing

Fig. 9

AP3S1 is involved in regulating the migratory capacity of ovarian cancer. A WGCNA analysis of genes correlated with AP3S1 expression and ovarian cancer clinical characteristic. B Significant inhibition of migration and metastasis ability in ovarian cancer cells after AP3S1 knockdown. C Scratch assay confirms that low AP3S1 expression weakens the migration ability of ovarian tumor cells. D The proliferation ability of ovarian cancer cells was inhibited after knocking down AP3S1. All data are mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. Representative data are from three independent experiments

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European Journal of Medical Research

ISSN: 2047-783X

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