Fig. 2

Biological characteristics and immune cell infiltration in four ion channel subtypes. A Gene set variation analysis to examine the differences in the biological function of four ion channel subtypes. Blue and red to represent the inhibition and activation of biological pathways respectively. B The analysis of Infiltration abundance of 28 immune cells in ion channel subtypes. (Kruskal–Wallis test, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001). C Differences in the TIDE scores among ion channel subtypes. D Differences in epithelial-mesenchymal transition and immune-related pathways among ion channel subtypes. (Kruskal–Wallis test, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001). TIDE tumor immune dysfunction and exclusion