Fig. 5

Evaluation of ion channel models. A Kaplan–Meier curve showing significant differences between high- and low-score groups in the TCGA (log-rank test, p < 0.0001). B The predictive ability of ion channel model for the 1-, 3-, and 5-year prognosis of CRC patients in the TCGA. C Differences in ion channel score among four subtypes. D Multivariate COX regression analysis of ion channel scores. E Comparison of the ion channel gene model with published prognostic models for CRC regarding 1, 3, and 5-year survival prediction. Ion.Sig as the model in this study. TCGA The Cancer Genome Atlas, CRC colorectal cancer