Fig. 8

Immunological characteristics and genomic differences between high- and low-score groups. A, B Waterfall plot to depict the differences in gene mutation landscape between high- (A) and low-score (B) groups. C Different expression of immune checkpoint genes in high- and low-score groups. D Differences in the TIDE scores between the low- and high-score groups in the TCGA dataset. E Scatterplots to exhibit a positive association between TIDE scores and ion channel scores in the CRC cohort (Spearman Correlation Coefficient; TCGA). TCGA The Cancer Genome Atlas, CRC colorectal cancer, TIDE tumor immune dysfunction and exclusion