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Table 2 Competing risk regression model of CVD and all-cause mortality based on the TyG-WC index quartiles TyG-WC index quartiles

From: Triglyceride-glucose-waist circumference index predicts the incidence of cardiovascular disease in Korean populations: competing risk analysis of an 18-year prospective study

 

TyG-WC index quartiles

Q1

Q2

Q3

Q4

(n = 1872)

(n = 1869)

(n = 1870)

(n = 1871)

Incident CVD, n

95

157

200

239

Follow-up, person-year

30474.5

29969.4

29610.3

29209.3

Incident rate per 1000 person-year (95% CI)

3.12 (2.49–3.75)

5.24 (4.42–6.06)

6.75 (5.81–7.69)

8.18 (7.14–9.22)

 

HR

HR

95% CI

P value

HR

95% CI

P value

HR

95% CI

P value

Risk of incident CVD

          

 Unadjusted

1 (ref.)

1.68

1.30–2.16

< 0.001

2.17

1.70–2.77

< 0.001

2.65

2.09–3.36

< 0.001

 Model 1

1 (ref.)

1.55

1.20–2.02

< 0.001

2.04

1.55–2.67

< 0.001

2.46

1.83–3.30

< 0.001

 Model 2

1 (ref.)

1.53

1.16–2.01

< 0.001

2.06

1.55–2.73

< 0.001

2.57

1.89–3.50

< 0.001

 Model 3

1 (ref.)

1.47

1.12–1.93

< 0.001

1.91

1.44–2.54

< 0.001

2.24

1.63–3.07

< 0.001

All-cause death, n

116

 

129

  

138

  

179

 

Follow-up, person-year

30474.5

 

29969.4

  

29610.3

  

29209.3

 

Incident rate per 1000 person-year (95% CI)

3.81(3.12-4.50)

4.30(3.56–5.04)

 

4.66(3.88–5.23)

 

6.13(5.23–7.03)

 

HR

HR

95% CI

P value

HR

95% CI

P value

HR

95% CI

P value

Risk of all-cause mortality

          

 Unadjusted

1 (ref.)

1.07

0.84–1.37

0.590

1.16

0.91–1.48

0.240

1.46

1.16–1.84

0.001

 Model 1

1 (ref.)

0.92

0.71–1.21

0.550

1.04

0.78–1.39

0.790

1.37

0.98–1.92

0.060

 Model 2

1 (ref.)

0.90

0.67–1.19

0.460

1.04

0.76–1.43

0.800

1.30

0.90–1.86

0.160

 Model 3

1 (ref.)

0.86

0.65–1.15

0.310

0.97

0.71–1.33

0.850

1.11

0.76–1.61

0.590

  1. Model 1: adjusted for sex, age and body mass index
  2. Model 2: adjusted for variables used in Model 1 plus residence, total energy intake, smoking status, drinking status and physical activity
  3. Model 3: adjusted for variables used in Model 2 plus mean blood pressure, fasting plasma glucose, serum total cholesterol, CRP and eGFR
  4. CVD, cardiovascular disease; HR, hazard ratio; CRP, C-reactive protein; eGFR, estimated glomerular filtration rate