Skip to main content

Table 1 The correlation between clinicopathological variables and FNDC3B expression in PC patients

From: Identification of fibronectin type III domain containing 3B as a potential prognostic and therapeutic target for pancreatic cancer: a preliminary analysis

Characteristics

Levels

Low expression of FNDC3B

High expression of FNDC3B

P

n

89

89

  

T stage, n (%)

T1

5 (2.8%)

2 (1.1%)

0.114

T2

14 (8%)

10 (5.7%)

 

T3

65 (36.9%)

77 (43.8%)

 

T4

3 (1.7%)

0 (0%)

 

N stage, n (%)

N0

33 (19.1%)

16 (9.2%)

0.004

N1

53 (30.6%)

71 (41%)

 

M stage, n (%)

M0

31 (36.9%)

49 (58.3%)

0.980

M1

1 (1.2%)

3 (3.6%)

 

Pathologic stage, n (%)

I

15 (8.6%)

6 (3.4%)

0.034

II

68 (38.9%)

79 (45.1%)

 

III

3 (1.7%)

0 (0%)

 

IV

1 (0.6%)

3 (1.7%)

 

Radiation therapy, n (%)

No

58 (35.6%)

60 (36.8%)

0.633

Yes

24 (14.7%)

21 (12.9%)

 

Primary therapy outcome, n (%)

PD

17 (12.1%)

33 (23.6%)

0.079

SD

6 (4.3%)

3 (2.1%)

 

PR

4 (2.9%)

6 (4.3%)

 

CR

39 (27.9%)

32 (22.9%)

 

Age, n (%)

≤ 65

38 (21.3%)

56 (31.5%)

0.007

> 65

51 (28.7%)

33 (18.5%)

 

Race, n (%)

Asian

6 (3.4%)

5 (2.9%)

0.972

Black or African American

3 (1.7%)

3 (1.7%)

 

White

80 (46%)

77 (44.3%)

 

Gender, n (%)

Female

42 (23.6%)

38 (21.3%)

0.547

Male

47 (26.4%)

51 (28.7%)

 

Histologic grade, n (%)

G1

24 (13.6%)

7 (4%)

0.001

G2

44 (25%)

51 (29%)

 

G3

17 (9.7%)

31 (17.6%)

 

G4

2 (1.1%)

0 (0%)

 

Residual tumor, n (%)

R0

59 (36%)

47 (28.7%)

0.056

R1

19 (11.6%)

34 (20.7%)

 

R2

3 (1.8%)

2 (1.2%)

 

Anatomic neoplasm subdivision, n (%)

Head

67 (37.6%)

72 (40.4%)

0.365

Other

22 (12.4%)

17 (9.6%)

 

Alcohol history, n (%)

No

29 (17.5%)

35 (21.1%)

0.280

Yes

55 (33.1%)

47 (28.3%)

 

Smoker, n (%)

No

40 (27.6%)

26 (17.9%)

0.133

Yes

38 (26.2%)

41 (28.3%)

 

History of chronic pancreatitis, n (%)

No

66 (46.5%)

63 (44.4%)

0.854

Yes

7 (4.9%)

6 (4.2%)

 

History of diabetes, n (%)

No

56 (38.1%)

53 (36.1%)

0.680

Yes

21 (14.3%)

17 (11.6%)

 
  1. Total patients’ number does not equal to 89 in all variates due to lack of patient’s information for some cases
  2. CR complete response, FNDC3B fibronectin type III domain containing 3B, G1: well-differentiated, G2: moderately-differentiated, G3: poorly-differentiated, G4: undifferentiated, M: metastasis, N: lymph node, PC pancreatic cancer, PR partial response, PD progressive disease, SD stable disease, T: tumor
  3. Bold values indicate that P < 0.05 which are statistically significant