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Table 3 Clinical and biochemical characteristics of the COVID-19 study cohort in the recovery phase of infection

From: Immunoglobulins in COVID-19 pneumonia: from the acute phase to the recovery phase

Variables

No Pneumoniaa

(WHO 1)

(n = 24)

Pneumoniab

(WHO 2–7)

(n = 228)

P-valuec

Male

12 (50)

141 (61.8)

0.259

Age, years

54 (40.7–62.5)

59 (50–68)

0.025

Hematological parameters

   

 Leukocytes (×10E9/L)

5.9 (4.8–6.5)

5.7 (4.7–7.3)

0.882

 Red blood cell count (×10E9/L)

4.6 (4–5.1)

4.5 (4.2–4.8)

0.395

 Hemoglobin (g/dL)

13.7 (12.2–14.8)

13.2 (12.2–14.3)

0.284

 Hematocrit (%)

42.5 (38.1–46)

41.3 (37.8–44)

0.218

 Platelet count (×10E9/L)

237.5 (184.2–284.2)

228.5 (189–283)

0.892

 Neutrophils (%)

56.2 (50–59)

54.5 (47.8–61.1)

0.896

 Lymphocytes (%)

33.7 (27.5–39.3)

31.5 (26–37.8)

0.309

 Total lymphocytes

1855 (1655–2517.5)

1815 (1440–2292.5)

0.193

 Monocytes (%)

8.3 (7.2–9.7)

8.8 (7.4–10.2)

0.411

Inflammatory markers

   

 d-Dimer (mg/L)

418.5 (297–696.7)

426 (331–686)

0.459

 Fibrinogen (g/L)

426 (352.7–462.5)

505.5 (426.7–592)

 < 0.001

 Interleukin 6 (pg/mL)d

2.7 (0.5–2.8)

2.2 (0.6–4)

0.770

 Ferritin (ng/mL)

129 (68–292.5)

180 (94–340)

0.185

 C Reactive Protein (mg/L)

0.2 (0–0.4)

0 (0–0.7)

0.831

Biochemical markers

   

 Glucose (mg/dL)

93.5 (85.5–107.5)

98.5 (89–114)

0.250

 Urea (mg/dL)

36 (27.7–47)

36 (29–44)

0.711

 Creatinine (mg/dL)

0.87 (0.8–0.9)

0.8 (0.7–1)

0.474

 Aspartate aminotransferase (AST) (U/L)

22 (19–27.2)

23 (18–28)

0.782

 Alanine aminotransferase (ALT) (U/L)

25 (19.7–34.2)

30 (21–46)

0.181

 Lactate dehydrogenase (LDH) (U/L)

193 (170–210)

197 (175–221)

0.333

  1. Data are presented as n (%) or median (25th–75th interquartile range)
  2. aThe No Pneumonia group refers to the ambulatory group comprising mild illness without pneumonia—WHO 1
  3. bThe Pneumonia group comprises mild illness with pneumonia—WHO 2–7
  4. cNo Pneumonia and Pneumonia groups were compared using the non-parametric Mann–Whitney test for continuous data and √χ2 test for categorical data. P-value < 0.05 was considered significant and marked in bold
  5. dIL-6 data were from 244 patients, WHO 1 n = 21 and WHO 2–7 n = 188