Fig. 4

Correlation between leukocyte GPR43 and NLRP3 mRNA expression and cardiac parameters. A, B Leukocyte GPR43 mRNA expression was negatively correlated to LAD and positively correlated to LVEF. Spearman’s correlation analysis. C, D Leukocyte NLRP3 mRNA expression was positively correlated to LAD and negatively correlated to LVEF. Spearman’s correlation analysis. E Interrelationship of intestinal SCFAs (e.g., acetic acid, butyric acid, caproic acid and valeric acid), leukocyte GPR43 and NLRP3 mRNA expression, LAD and AF. The significant correlations using Spearman’s correlation analysis were depicted in the correlation network. *P < 0.05; **P < 0.01, ***P < 0.001