Unveilling genetic profiles and correlations of biofilm-associated genes, quorum sensing, and antibiotic resistance in Staphylococcus aureus isolated from a Malaysian Teaching Hospital

Table 5 Association between the presences of agrI with antibiotic susceptibility in S. aureus clinical isolates

Antibiotics	Susceptibility	No of isolates		p value
Antibiotics	Susceptibility	agrI	Non agrI	p value
Clindamycin	S	41	42	0.002*
	R	7	8
	IR	21	3
Erythromycin	S	41	40	0.082*
	R	28	13	0.082*
Gentamicin	S	61	41	0.259
	R	7	9
	IN	1	3
Oxacillin	S	25	43	0.000*
	R	44	10	0.000*
Penicillin	S	10	12	0.342
	R	59	41	0.342
Rifampicin	S	68	53	1.000
	R	1	0	1.000
Cotrimoxazole	S	61	44	0.437
	R	8	9	0.437
Tetracycline	S	64	39	0.005*
	R	5	14	0.005*
Ciprofloxacin	S	31	44	0.000*
	R	38	9	0.000*
Levofloxacin	S	31	45	0.000*
	R	38	8	0.000*
Moxifloxacin	S	27	39	0.000*
	R	35	6
	IN	3	2

Linezolid and vancomycin were excluded from the analysis as all S. aureus isolates were susceptible to these antibiotics. S: susceptible; R: resistant; IR: inducible resistant; IN: intermediate, *p < 0.05 indicates significant difference between groups

ISSN: 2047-783X