Volume 19 Supplement 1

Proceedings of the 1st International Conference of Collaborative Research Center 974: Liver Damage and Regeneration

Meeting Abstracts

Edited by Dieter Häussinger and Helmut Sies

Publication of this supplement has been funded by the Deutsche Forschungsgemeinschaft (DFG) through Collaborative Research Center SFB 974 (Düsseldorf, Germany). The Supplement Editors declare that they have no competing interests.

1st International Conference of Collaborative Research Center 974: Liver Damage and Regeneration. Go to conference site.

Düsseldorf, Germany15-16 November 2013

Concatenated PDF 19S1

Preface

Authors: Dieter Häussinger and Helmut Sies

Citation: European Journal of Medical Research 2014 19(Suppl 1):I1

Content type: Introduction Published on: 19 June 2014
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Regenerative responses to liver injury

Authors: George K Michalopoulos

Citation: European Journal of Medical Research 2014 19(Suppl 1):S1

Content type: Meeting abstract Published on: 19 June 2014
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Endothelial cell-derived signals in liver development and regeneration

Authors: Eckhard Lammert, Jennifer Axnick and Tobias Buschmann

Citation: European Journal of Medical Research 2014 19(Suppl 1):S2

Content type: Meeting abstract Published on: 19 June 2014
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The role of the lymphotoxin-β receptor (LTβR) in hepatocyte-mediated liver regeneration

Authors: Kristina Behnke, Ursula R Sorg, Diran Herebian, Dieter Häussinger, Verena Keitel and Klaus Pfeffer

Citation: European Journal of Medical Research 2014 19(Suppl 1):S3

Content type: Meeting abstract Published on: 19 June 2014
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Hedgehog signalling in liver regeneration

Authors: Anna Diehl

Citation: European Journal of Medical Research 2014 19(Suppl 1):S4

Content type: Meeting abstract Published on: 19 June 2014
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Hepato-biliary stem cells: facts and fancies

Authors: Neil D Theise

Citation: European Journal of Medical Research 2014 19(Suppl 1):S5

Content type: Meeting abstract Published on: 19 June 2014
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Stellate cells are mesenchymal stem cells

Authors: Claus Kordes, Iris Sawitza, Silke Götze, Diran Herebian and Dieter Häussinger

Citation: European Journal of Medical Research 2014 19(Suppl 1):S6

Content type: Meeting abstract Published on: 19 June 2014
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Epigenetic regulation during hepatic stellate cell activation

Authors: Silke Götze, Eva Quenkert, Claus Kordes, Iris Sawitza and Dieter Häussinger

Citation: European Journal of Medical Research 2014 19(Suppl 1):S7

Content type: Meeting abstract Published on: 19 June 2014
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Characterisation of human induced pluripotent stem cell-derived hepatocyte-like cells and endodermal progenitors

Authors: Peggy Matz and James Adjaye

Citation: European Journal of Medical Research 2014 19(Suppl 1):S8

Content type: Meeting abstract Published on: 19 June 2014
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The non-structural protein 5A (NS5A) of hepatitis C virus interacts with the SH3 domain of human Bin1 using non-canonical binding sites

Authors: Melanie Schwarten, Zsófia Sólyom, Sophie Feuerstein, Amine Aladağ, Silke Hoffmann, Dieter Willbold and Bernhard Brutscher

Citation: European Journal of Medical Research 2014 19(Suppl 1):S9

Content type: Meeting abstract Published on: 19 June 2014
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Analysis of the Bin1 SH3 interaction with peptides derived from the hepatitis C virus protein NS5A and c-Myc reveals that NS5A can competitively displace c-Myc in vitro

Authors: Amine Aladağ, Christina Bösing, Lothar Gremer, Silke Hoffmann, Stefan Klinker, Melanie Schwarten, Matthias Stoldt, Olga Valdau and Dieter Willbold

Citation: European Journal of Medical Research 2014 19(Suppl 1):S10

Content type: Meeting abstract Published on: 19 June 2014
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Atomic force measurements on the specifically orientated membrane protein TGR5 reconstituted inside a tethered bilayer lipid membrane

Authors: Anna Bronder, Arpita Roychoudhury, Dieter Häussinger and Filipp Oesterhelt

Citation: European Journal of Medical Research 2014 19(Suppl 1):S11

Content type: Meeting abstract Published on: 19 June 2014
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High-precision FRET analysis of the G-protein coupled receptor TGR5 in live cells

Authors: Annemarie Koch, Qijun Ma, Manuel Frohnapfel, Lina Spomer, Verena Keitel-Anselmino, Christoph Gertzen, Holger Gohlke and Claus AM Seidel

Citation: European Journal of Medical Research 2014 19(Suppl 1):S12

Content type: Meeting abstract Published on: 19 June 2014
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α₅β₁ integrins in hepatocytes act as receptors for bile acids with a (nor)ursodeoxycholane scaffold

Authors: Michele Bonus, Annika Sommerfeld, Dieter Häussinger and Holger Gohlke

Citation: European Journal of Medical Research 2014 19(Suppl 1):S13

Content type: Meeting abstract Published on: 19 June 2014
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The secondary structure of the TGR5 membrane-proximal C-terminus determines plasma membrane localization and responsiveness towards extracellular ligands

Authors: Christoph Gertzen, Lina Spomer, Birte Schmitz, Dieter Häussinger, Verena Keitel and Holger Gohlke

Citation: European Journal of Medical Research 2014 19(Suppl 1):S14

Content type: Meeting abstract Published on: 19 June 2014
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Glutamine synthetase mutations that cause glutamine deficiency: mechanistic insights from molecular dynamics simulations

Authors: Benedikt Frieg, Nadine Homeyer, Dieter Häussinger and Holger Gohlke

Citation: European Journal of Medical Research 2014 19(Suppl 1):S15

Content type: Meeting abstract Published on: 19 June 2014
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New mechanisms involving the EGFR and FGF15/19 systems in liver regeneration and carcinogenesis

Authors: Carmen Berasain and Matías A Avila

Citation: European Journal of Medical Research 2014 19(Suppl 1):S16

Content type: Meeting abstract Published on: 19 June 2014
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Control and consequences of IL-6 receptor ectodomain shedding

Authors: Jürgen Scheller

Citation: European Journal of Medical Research 2014 19(Suppl 1):S17

Content type: Meeting abstract Published on: 19 June 2014
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In vitro investigations of ABC transporters of the human liver – advantages and surprises

Authors: Lutz Schmitt

Citation: European Journal of Medical Research 2014 19(Suppl 1):S18

Content type: Meeting abstract Published on: 19 June 2014
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Identification of new interaction partners of the human ABC transporter MDR3

Authors: Marianne Kluth, Katja Döhl, Philipp Ellinger, Susanne Przybylla, Sander Smits and Lutz Schmitt

Citation: European Journal of Medical Research 2014 19(Suppl 1):S19

Content type: Meeting abstract Published on: 19 June 2014
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Posttranslational regulation of the bile salt export pump

Authors: Susanne Przybylla and Lutz Schmitt

Citation: European Journal of Medical Research 2014 19(Suppl 1):S20

Content type: Meeting abstract Published on: 19 June 2014
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Role of the bile acid receptor TGR5 (Gpbar-1) in liver damage and regeneration

Authors: Verena Keitel, Maria Reich, Annika Sommerfeld, Stefanie Kluge, Ralf Kubitz and Dieter Häussinger

Citation: European Journal of Medical Research 2014 19(Suppl 1):S21

Content type: Meeting abstract Published on: 19 June 2014
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Mechanisms of tauroursodeoxycholate-mediated inhibition of apoptosis

Authors: Annika Sommerfeld, Patrick GK Mayer, Roland Reinehr and Dieter Häussinger

Citation: European Journal of Medical Research 2014 19(Suppl 1):S22

Content type: Meeting abstract Published on: 19 June 2014
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Role of primary bile salts in the regulation of sinusoidal substrate uptake in rat liver

Authors: Stefanie Kluge, Olga Domanova, Thomas Berlage, Dieter Häussinger and Ralf Kubitz

Citation: European Journal of Medical Research 2014 19(Suppl 1):S23

Content type: Meeting abstract Published on: 19 June 2014
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Crucial role of the MAPKAP kinases 2 and 3 for pathogen-induced inflammation and their relevance for the immune response of the liver

Authors: Christian Ehlting, Dieter Häussinger and Johannes G Bode

Citation: European Journal of Medical Research 2014 19(Suppl 1):S24

Content type: Meeting abstract Published on: 19 June 2014
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Immune functions during chronic viral infections

Authors: Philipp Lang, Dieter Häussinger and Karl S Lang

Citation: European Journal of Medical Research 2014 19(Suppl 1):S25

Content type: Meeting abstract Published on: 19 June 2014
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Enforced viral replication, a mechanism for immune activation

Authors: Karl S Lang, Nadine Honke, Namir Shaabani, Dieter Häussinger and Philipp A Lang

Citation: European Journal of Medical Research 2014 19(Suppl 1):S26

Content type: Meeting abstract Published on: 19 June 2014
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Bile acid-induced modulation of virus replication

Authors: Anna-Kathrin Schupp and Dirk Graf

Citation: European Journal of Medical Research 2014 19(Suppl 1):S27

Content type: Meeting abstract Published on: 19 June 2014
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Absolute GABA spectroscopy with MEGA-PRESS and watermapping in sensorimotor and visual cortex and correlation to handedness

Authors: Georg Oeltzschner, Nienke Hoogenboom, Thomas Baumgarten, Hans-Jörg Wittsack and Alfons Schnitzler

Citation: European Journal of Medical Research 2014 19(Suppl 1):S28

Content type: Meeting abstract Published on: 19 June 2014
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Protein oxidative damage in the hippocampus in a mouse model of acute hyperammonemia

Authors: Jasmin Klose, Boris Goerg, Carsten Berndt, Dieter Häussinger, Orhan Aktas and Tim Prozorovski

Citation: European Journal of Medical Research 2014 19(Suppl 1):S29

Content type: Meeting abstract Published on: 19 June 2014
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Proceedings of the 1st International Conference of Collaborative Research Center 974: Liver Damage and Regeneration

Meeting Abstracts

Preface

Regenerative responses to liver injury

Endothelial cell-derived signals in liver development and regeneration

The role of the lymphotoxin-β receptor (LTβR) in hepatocyte-mediated liver regeneration

Hedgehog signalling in liver regeneration

Hepato-biliary stem cells: facts and fancies

Stellate cells are mesenchymal stem cells

Epigenetic regulation during hepatic stellate cell activation

Characterisation of human induced pluripotent stem cell-derived hepatocyte-like cells and endodermal progenitors

The non-structural protein 5A (NS5A) of hepatitis C virus interacts with the SH3 domain of human Bin1 using non-canonical binding sites

Analysis of the Bin1 SH3 interaction with peptides derived from the hepatitis C virus protein NS5A and c-Myc reveals that NS5A can competitively displace c-Myc in vitro

Atomic force measurements on the specifically orientated membrane protein TGR5 reconstituted inside a tethered bilayer lipid membrane

High-precision FRET analysis of the G-protein coupled receptor TGR5 in live cells

α₅β₁ integrins in hepatocytes act as receptors for bile acids with a (nor)ursodeoxycholane scaffold

The secondary structure of the TGR5 membrane-proximal C-terminus determines plasma membrane localization and responsiveness towards extracellular ligands

Glutamine synthetase mutations that cause glutamine deficiency: mechanistic insights from molecular dynamics simulations

New mechanisms involving the EGFR and FGF15/19 systems in liver regeneration and carcinogenesis

Control and consequences of IL-6 receptor ectodomain shedding

In vitro investigations of ABC transporters of the human liver – advantages and surprises

Identification of new interaction partners of the human ABC transporter MDR3

Posttranslational regulation of the bile salt export pump

Role of the bile acid receptor TGR5 (Gpbar-1) in liver damage and regeneration

Mechanisms of tauroursodeoxycholate-mediated inhibition of apoptosis

Role of primary bile salts in the regulation of sinusoidal substrate uptake in rat liver

Crucial role of the MAPKAP kinases 2 and 3 for pathogen-induced inflammation and their relevance for the immune response of the liver

Immune functions during chronic viral infections

Enforced viral replication, a mechanism for immune activation

Bile acid-induced modulation of virus replication

Absolute GABA spectroscopy with MEGA-PRESS and watermapping in sensorimotor and visual cortex and correlation to handedness

Protein oxidative damage in the hippocampus in a mouse model of acute hyperammonemia

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