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  1. Small cell bladder cancer (SCBC) is an aggressive subtype accounting for less than 1 % of all bladder malignancies associated with rapid progression, early metastases formation and high mortality rates.

    Authors: Isabel Heidegger, Gennadi Tulchiner, Georg Schäfer, Wolfgang Horninger and Renate Pichler
    Citation: European Journal of Medical Research 2016 21:40
  2. Multiple trauma is often accompanied by systemic inflammatory response syndrome (SIRS). The aim of this study was to investigate the impact of polymeric plasma substitutes on the development of SIRS or sepsis.

    Authors: Kai Sprengel, Hanspeter Simmen, Clément M. L. Werner, Simon Sulser, Michael Plecko, Catharina Keller and Ladislav Mica
    Citation: European Journal of Medical Research 2016 21:39
  3. Graft-versus-host disease (GVHD) after liver and kidney transplantation has high mortality and causes diagnostic challenges. This study aims to describe the cytokine and human leukocyte antigen (HLA) profile i...

    Authors: Xinhua Chen, Xueqin Meng, Yuning Xu, Haiyang Xie, Shengyong Yin, Hongchun Li, Liming Wu and Shusen Zheng
    Citation: European Journal of Medical Research 2016 21:38

    The Erratum to this article has been published in European Journal of Medical Research 2017 22:37

  4. Although under discussion, induced hypothermia (IH) is an established therapy for patients with cardiac arrest or traumatic brain injuries. The influences on coagulopathy and bleeding tendency in severely inju...

    Authors: Kai Oliver Jensen, Leonhard Held, Andrea Kraus, Frank Hildebrand, Philipp Mommsen, Ladislav Mica, Guido A. Wanner, Peter Steiger, Rudolf M. Moos, Hans-Peter Simmen and Kai Sprengel
    Citation: European Journal of Medical Research 2016 21:37
  5. Anterior tibial pseudoaneurysm is a rare complication after interlocking screw insertion in tibial nailing. We present the case of a 28-year-old male patient with this complication with a 6-week delay after ti...

    Authors: F. Greve, M. Crönlein, M. Beirer, C. Kirchhoff, P. Biberthaler and K. F. Braun
    Citation: European Journal of Medical Research 2016 21:36
  6. Readmissions are a burden for patients and increase healthcare costs. In Europe, factors associated with readmissions have not yet been extensively investigated. This study aimed to discover factors associated...

    Authors: Fabienne J. H. Magdelijns, Larissa Schepers, Evelien Pijpers, Coen D. A. Stehouwer and Patricia M. Stassen
    Citation: European Journal of Medical Research 2016 21:35
  7. Anterior cervical discectomy and fusion (ACDF) is one of the most prevalent spine surgeries and neurosurgical procedures performed to treat a variety of disorders in the cervical spine. Over the last several y...

    Authors: Dexiang Ban, Yang Liu, Taiwei Cao and Shiqing Feng
    Citation: European Journal of Medical Research 2016 21:34
  8. Pycnodysostosis is an autosomal recessive skeletal dysplasia, the prevalence of which is estimated to be low (1 per million). Nevertheless, in recent years we have found 27 affected individuals from 22 familie...

    Authors: Thaís Fenz Araujo, Erlane Marques Ribeiro, Anderson Pontes Arruda, Carolina Araujo Moreno, Paula Frassinetti Vasconcelos de Medeiros, Renata Moldenhauer Minillo, Débora Gusmão Melo, Chong Ae Kim, Maria Juliana Rodovalho Doriqui, Têmis Maria Felix, Rodrigo Ambrosio Fock and Denise Pontes Cavalcanti
    Citation: European Journal of Medical Research 2016 21:33
  9. Postoperative radiotherapy after breast-conserving surgery (BCS) is the standard in the management of breast cancer. The optimal timing for starting postoperative radiation therapy has not yet been well define...

    Authors: Raffaella Caponio, Maria Paola Ciliberti, Giusi Graziano, Rocco Necchia, Giovanni Scognamillo, Antonio Pascali, Sabino Bonaduce, Anna Milella, Gabriele Matichecchia, Cristian Cristofaro, Davide Di Fatta, Pasquale Tamborra and Marco Lioce
    Citation: European Journal of Medical Research 2016 21:32
  10. The stem cell as the building block necessary for tissue reparation and homeostasis plays a major role in regenerative medicine. Their unique property of being pluripotent, able to control immune process and e...

    Authors: Felix Dyrna, Elmar Herbst, Alexander Hoberman, Andreas B. Imhoff and Andreas Schmitt
    Citation: European Journal of Medical Research 2016 21:29
  11. Studies have been reported that cyclin-dependent kinase5 (CDK5) was associated with the development of several cancers. However, the relationship between CDK5 level and clinicopathological factors is still poo...

    Authors: Deng-Hua Pan, Mei-Lin Zhu, Xiao-Miao Lin, Xing-Gu Lin, Rong-Quan He, Yan-Xin Ling, Shi-Tao Su, Madushi Mihiranganee Wickramaarachchi, Yi-Wu Dang, Kang-Lai Wei and Gang Chen
    Citation: European Journal of Medical Research 2016 21:28
  12. Tarsoconjunctival flap advancement, or the Hughes procedure, is among the techniques of choice for reconstructing full-thickness lower eyelid defects so as to restore normal anatomy and function with the best ...

    Authors: Ahmed M. Hishmi, Konrad R. Koch, Mario Matthaei, Edwin Bölke, Claus Cursiefen and Ludwig M. Heindl
    Citation: European Journal of Medical Research 2016 21:27
  13. Histone deacetylation, a common hallmark in malignant tumors, strongly alters the transcription of genes involved in the control of proliferation, cell survival, differentiation and genetic stability. We have ...

    Authors: Reena Buurman, Maria Sandbothe, Brigitte Schlegelberger and Britta Skawran
    Citation: European Journal of Medical Research 2016 21:26
  14. Neoadjuvant radio chemotherapy and immediate reconstruction for breast cancer are still under debate. But there are recent abstracts and articles which show that neoadjuvant radio chemotherapy is feasible and ...

    Authors: Carolin Nestle-Krämling, Edwin Bölke, Wilfried Budach and Christoph Andree
    Citation: European Journal of Medical Research 2016 21:24

    The Erratum to this article has been published in European Journal of Medical Research 2016 21:30

  15. It has been previously postulated that high phenylalanine (Phe) might disturb intracerebral dopamine production, which is the main regulator of prolactin secretion in the pituitary gland. Previously, various a...

    Authors: Eszter Juhász, Erika Kiss, Erika Simonova, Attila Patócs and Peter Reismann
    Citation: European Journal of Medical Research 2016 21:22
  16. Despite substantial advances in the imaging techniques and pathophysiological understanding over the last decades, identification of the underlying causes of left ventricular hypertrophy by means of echocardio...

    Authors: Dan Liu, Kai Hu, Peter Nordbeck, Georg Ertl, Stefan Störk and Frank Weidemann
    Citation: European Journal of Medical Research 2016 21:21
  17. Pulmonary cavitation is the classic hallmark of pulmonary tuberculosis (PTB) and is the site of very high mycobacterial burden associated with antimycobacterial drug resistance and treatment failure. The objec...

    Authors: Qiusheng Huang, Yongmei Yin, Shougang Kuai, Yan Yan, Jun Liu, YingYing Zhang, Zhongbao Shan, Lan Gu, Hao Pei and Jun Wang
    Citation: European Journal of Medical Research 2016 21:20
  18. Pierson syndrome (PS) is a rare autosomal recessive disorder, caused by mutations in the laminin β2 (LAMB2) gene. It is characterized by congenital nephrotic syndrome, microcoria, and neurodevelopmental defici...

    Authors: Boutaina Zemrani, François Cachat, Olivier Bonny, Eric Giannoni, Jacques Durig, Florence Fellmann and Hassib Chehade
    Citation: European Journal of Medical Research 2016 21:19
  19. To assess clinical application of computed tomography (CT)-guided 125I seed implantation for patients who cannot endure or unwillingly receive repeated surgery, chemotherapy, or radiotherapy for unmanageable cerv...

    Authors: Hai Huang, Shaonian Xu, Fusheng Li, Zhenguang Du and Liang Wang
    Citation: European Journal of Medical Research 2016 21:18
  20. Lung cancer is one of the most preventable causes of death globally both in developed and developing countries. Although it is well established that smokers develop lung cancer, there are some smokers who are ...

    Authors: Vidyullatha Peddireddy, Siva Prasad Badabagni, Sandhya Devi Gundimeda, Vasudha Mamidipudi, Pardhanandana Reddy Penagaluru and Hema Prasad Mundluru
    Citation: European Journal of Medical Research 2016 21:17
  21. Hepatitis, a highly contagious viral infection, is one of the leading killer diseases globally caused by hepatitis virus. Among the existing viral causes for hepatic failure, hepatitis B virus (HBV) plays a si...

    Authors: Zelalem Desalegn, Liya Wassie, Habtamu Bedimo Beyene, Adane Mihret and Yehenew A. Ebstie
    Citation: European Journal of Medical Research 2016 21:16
  22. Isolated radial neck fractures occur only in rare cases. The majority of cases are non-displaced or minimally displaced and can be treated conservatively. Conservative treatment, however, might result in secon...

    Authors: G. H. Sandmann, M. Crönlein, M. Neumaier, M. Beirer, A. Buchholz, U. Stöckle, P. Biberthaler and S. Siebenlist
    Citation: European Journal of Medical Research 2016 21:15
  23. Vitamin D has immuno-modulatory properties, and deficient levels of circulating 25-hydroxyvitamin D (<30 nmol/l) may contribute to increased risk of infectious illnesses. This narrative review summarises data ...

    Authors: Armin Zittermann, Stefan Pilz, Harald Hoffmann and Winfried März
    Citation: European Journal of Medical Research 2016 21:14
  24. Overlengthening by radial head prosthetic replacement leads to insufficient functionality and increased capitellar wear. It has been shown that in monopolar prostheses, the radial overlengthening by an overstu...

    Authors: Kilian Wegmann, Wei Zhang, Volker Strauss, Christian Ries, Lars P. Müller and Klaus J. Burkhart
    Citation: European Journal of Medical Research 2016 21:12
  25. To analyse the timing of cardiac troponin (cTn) measurements in high-risk and cTn-positive acute coronary syndromes without persistent ST-segment elevation (NSTE-ACS) in two structurally different German chest...

    Authors: Dieter Fischer, Friederike Remberg, Dirk Böse, Michael Lichtenberg, Philipp Kümpers, Pia Lebiedz, Hermann-Joseph Pavenstädt, Johannes Waltenberger and Frank Breuckmann
    Citation: European Journal of Medical Research 2016 21:11
  26. Pathological examination combined with tumor markers has become a standard for the diagnosis of intracranial germ cell tumors (ICGCTs), but the current concept of ‘secreting germ cell tumors’ and three empiric...

    Authors: Mingming Hu, Hongzhi Guan, Ching C. Lau, Keita Terashima, Zimeng Jin, Liying Cui, Yuzhou Wang, Guilin Li, Yong Yao, Yi Guo, Yan Michael Li, Dingrong Zhong, Juan Xiao, Xirun Wan, Xin Lian, Feng Feng…
    Citation: European Journal of Medical Research 2016 21:10
  27. Diaphragm motion during spontaneous or mechanical respiration hinders image-guided percutaneous interventions of tumours in lung and upper abdomen. Motion-tracking methods can be applied but increase procedure...

    Authors: Thomas Günther Lesser, Harald Schubert, Daniel Güllmar, Jürgen R. Reichenbach and Frank Wolfram
    Citation: European Journal of Medical Research 2016 21:9
  28. The rabbit disc model is useful for the study of intervertebral disc (IVD) degeneration and experimental therapeutic interventions. The annulotomy-induced disc models present several drawbacks, particularly an...

    Authors: Long Xin, Chun Zhang, Fuhua Zhong, Shunwu Fan, Wei Wang and Zhenbin Wang
    Citation: European Journal of Medical Research 2016 21:7
  29. Over the past 60 years, hyaluronidase has been successfully utilized in ophthalmic surgery and is now being implemented in dermatosurgery as well as in other surgical disciplines. The enzyme is considered a “s...

    Authors: Bettina Alexandra Buhren, Holger Schrumpf, Norman-Philipp Hoff, Edwin Bölke, Said Hilton and Peter Arne Gerber
    Citation: European Journal of Medical Research 2016 21:5
  30. Laparoscopic Surgery has become a worldwide standard procedure for a variety of indications. This has been attributed to a milder postoperative inflammatory response by the innate immune system potentially med...

    Authors: Philipp Lingohr, Jonas Dohmen, Hanno Matthaei, Nils Konieczny, Juliane Hoffmann, Edwin Bölke, Sven Wehner and Jörg C. Kalff
    Citation: European Journal of Medical Research 2016 21:4
  31. Focal colorectal uptake in 18FDG-PET/CT may be associated with a malignancy and can be quantified. This provides the basis for an automatic trigger threshold above which cases are flagged for colonoscopic evaluat...

    Authors: Wolfgang Luboldt, Baerbel Wiedemann, Sebastian Fischer, Boris Bodelle, Hans Joachim Luboldt, Frank Grünwald and Thomas J. Vogl
    Citation: European Journal of Medical Research 2016 21:2
  32. The study investigated the feasibility and potential outcome measures during acute hyperoxia in type 2 diabetes patients (DM2).

    Authors: Robert Rozenberg, Robert T. Mankowski, Luc J. C. van Loon, Janneke G. Langendonk, Eric J. G. Sijbrands, Anton H. van den Meiracker, Henk J. Stam and Stephan F. E. Praet
    Citation: European Journal of Medical Research 2016 21:1
  33. We aim to illustrate the potential viability of MCTD as an underlying aetiology of Melkersson–Rosenthal syndrome. The case is probably the first description available in the literature of the Melkersson–Rosen...

    Authors: Dorota Jasinska and Jerzy Boczon
    Citation: European Journal of Medical Research 2015 20:100
  34. Diagnosis and treatment of stress fractures still remains to be a clinical and radiological challenge. Therapeutic options vary from conservative treatment to surgical treatment without a clear treatment conce...

    Authors: Moritz Crönlein, Isabel Rauscher, Ambros J. Beer, Markus Schwaiger, Christoph Schäffeler, Marc Beirer, Stephan Huber, Gunther H. Sandmann, Peter Biberthaler, Matthias Eiber and Chlodwig Kirchhoff
    Citation: European Journal of Medical Research 2015 20:99
  35. Interleukin 17 (IL-17) is a proinflammatory cytokine produced by a new subset of activated CD4+ T cells, Th17 cells. We previously showed that increased Th17 cell populations were presented in human medullobla...

    Authors: Ping Zhou, Qilin Zhang, Yao Zhao, Hongying Sha, Xiaoyun Cao and Yongfei Wang
    Citation: European Journal of Medical Research 2015 20:98
  36. Adenoid cystic carcinoma (ACC) is a rare malignant tumor that might occur in nasal cavity and paranasal sinuses. It is characteristic for poor prognosis, especially the solid histopathological subtype of the t...

    Authors: Piotr Wardas, Michał Tymowski, Agnieszka Piotrowska-Seweryn, Wojciech Kaspera, Aleksandra Ślaska-Kaspera and Jarosław Markowski
    Citation: European Journal of Medical Research 2015 20:97
  37. There are two major theories describing the pathophysiology of migraines. Vascular theory explains that migraines resulted from vasodilation of meningeal vessels irritating the trigeminal nerves and causing pa...

    Authors: Ahmadreza Pourshoghi, Arash Danesh, David Stuart Tabby, John Grothusen and Kambiz Pourrezaei
    Citation: European Journal of Medical Research 2015 20:96
  38. Colon cancer is a frequently occurring primary malignant tumor. Chemotherapy can reduce the risk of local and distant relapse. Therefore, it is very important to find new biomarkers that can predict chemoresis...

    Authors: Jinsong Hu, Ye Xu and Sanjun Cai
    Citation: European Journal of Medical Research 2015 20:95
  39. Male breast carcinoma (MBC) is rarely encountered in clinical practice. Due to its paucity, our knowledge of MBC only rely on small or single-institutional studies and sporadic cases. The current guidelines fo...

    Authors: Min Liu, Qiang Wang, Bin Liu, Ling Gao, Di Wu, Shuo Yang, Bailong Liu and Lihua Dong
    Citation: European Journal of Medical Research 2015 20:94
  40. The purpose of the present study was to investigate the influence of the pronator quadratus (PQ) muscle repair following volar plate fixation of distal radius fractures with special regards to the forearm pron...

    Authors: Sandra Häberle, Gunther Hubertus Sandmann, Stephan Deiler, Tobias Maximilian Kraus, Florian Fensky, Tobias Torsiglieri, Ina-Christine Rondak, Peter Biberthaler, Ulrich Stöckle and Sebastian Siebenlist
    Citation: European Journal of Medical Research 2015 20:93
  41. To evaluate the clinical value of plain magnetic resonance (MR) imaging (including magnetic resonance cholangiopancreatography, MRCP) and coronal liver acquisition with volume acceleration (LAVA) technique in ...

    Authors: Nana Sun, Qing Xu, Xisheng Liu, Wei Liu and Jianwei Wang
    Citation: European Journal of Medical Research 2015 20:92
  42. Placenta accreta is a rare obstetric condition but can lead to life-threatening complications that was mainly diagnosed in the third trimester. We present a case of acute trophoblastic pulmonary embolism (PE) ...

    Authors: Qiu-ming Wang, Hui-li Liu and Qun Dang
    Citation: European Journal of Medical Research 2015 20:91

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