A tribute to Professor Wolfgang Traugott Ulmer
- Janusz Kowalski1
© I. Holzapfel Publishers 2010
Published: 4 November 2010
After the War, Prof. Ulmer did medical educational courses at the Faculty of Medicine of Heidelberg University during 1946-1952. After completing the studies, he began his clinical carrier as an assistant in a clinic of internal medicine directed by Prof. Karla Matthes, who directs the young doctor's interests toward the pathologies of the respiratory system, and, in particular, commissions Prof. Ulmer to set up a pulmonary lab for testing lung function in the academic environment of Heidelberg. The young doctor gets short-term trainings in foreign medical centers, in Groningen in the Netherlands, with Prof. N.G.M. Orie, in Zurich in Switzerland, with Prof. P.H. Rossier, and later in the US as well.
Prof. Ulmer's scientific, teaching, and practical medical work develops at a fast space. His early achievements consist of the elaboration of a method to analyze oxygen and carbon dioxide in the exhaled air, with fast responding analyzers [1–3]; the latter being later termed capnograph. In the area of respiratory mechanics, he became instrumental in popularization whole body plethysmography in Germany to study airway resistance in the bronchial tree and gas thoracic capacity after a quiet exhalation [4, 5], with the use of a Bodytest apparatus. The methodology turned out later, and still is to-date, essential for the studies of bronchodilation and reversibility of bronchospasm of various etiology. Another early achievement of Prof. Ulmer had been the initiation of clinically-oriented studies of lung compliance; which is the ability of the lungs to stretch during volume changes relative to applied changes in pressure. That triggered a flurry of functional studies, now being tenets in the respiratory pathophysiology, demonstrating, among other things, increased lung compliance in obstructive and decreased in restrictive pathologies [6–11].
In the early 1970s, Prof. Ulmer becomes head of a clinic of respiratory diseases in Bochum; the region of Germany heavily involved with coal mining industry. The new position motivates Prof. Ulmer to broaden his clinical and research interests which now evolve toward occupational lung diseases [12, 13]. He is one of the first to point out that respiratory disability in silicosis is underlain not so much by fibrotic changes seen in radiograms as by increased airway resistance and lung emphysema . His another outstanding achievement has been the introduction of anticholinergics [15, 16], such as ipratropium bromide, and β2-agonists, such as fenoterol, and also the combination thereof - Berodual, in a metered dose inhalers, into the palette of bronchodilating medicines; these therapies provide an improvement in lung function and health status, and by doing so substantially extend the life span of coal miners.
At about the same time, Prof. Ulmer undertook close and sustained for the following years collaborations with the Polish respiratory counterparts such as the Clinic of Respiratory Diseases of Medical University in Warsaw, with the Department of Respiratory Physiopathology of the National Institute of Tuberculosis and Lung Diseases in Warsaw, and with the Clinic of Internal Diseases of the Medical University in Lublin.
During the time of Marshal Law in Poland, 1981-1983, a number of young Polish doctors from the cities of Warsaw and Lublin undertook clinical training courses in Prof. Ulmer's clinic of respiratory diseases in Bochum. Another significant form of bilateral collaboration consisted of Polish-German meetings organized alternately in Germany and Poland. Prof. Ulmer also initiated collaborative studies with a clinic of internal medicine in Lublin, headed at the time by Prof. J. Hanzlik, regarding the analysis of pulmonary function in miners of a newly constructed coal mine in Bogdanka [17, 18]. The findings of that study confirmed earlier findings  that not so much silica dust as cigarette smoking was the main underlying reason of disorders of pulmonary mechanics in miners.
Prof. Ulmer often stressed his ties to Poland and a desire to having his part in the development of modern pulmonary medicine in Poland. His attitude undoubtedly stemmed from, and was strengthened by, the Polish roots of his Mother, who was born in the city of Lodz, and by the Christian virtues of his Father, Prof. Friderick Ulmer, an evangelic theologist, who was banned to teach students at the Heidelberg University and to have sermons to worshippers during religious services during the World War II, due to his critical, publically expressed, remarks on the Nazis. Prof. Ulmer passed away in Bochum on September 17, 2009 at the age of 85.
Prof. Ulmer was arguably for decades the most eminent European respiratory scientist and clinician in the second half of the 20th century. He published over 450 articles, noted in international indexes, and edited many books. His active publishing spanned the years 1955-2004, when he wrote his last updates on the lung pathophysiology [19, 20]. His scientific insights into the field of respiration have led to many advances which are greatly appreciated to-date. He also was an empathic person to younger clinical fellows, which gained him many, many friends.
As a token of appreciation of Prof. Ulmer's contributions to the development of Polish pulmonology, he received honorary membership of the Polish Respiratory Society and earned a Doctor Honoris Causa degree rendered by the University of Lublin in Poland for his outstanding contributions to medicine.
Conflicts of interest
The authors declare that they have no competing interests.
- Matthes K, Ulmer W: Research on the analysis of the oxygen effect on patients with arterial hypoxemia. Dtsch Arch Klin Med 1955,202(5):548–58. (Article in German)PubMedGoogle Scholar
- Ulmer WT, Prugger H, Bruck A: A fast recording oxygen measurement apparatus for continuous registration of oxygen concentration in the respiratory air. Pflügers Arch Gesamte Physiol Menschen Tiere 1960, 270: 536–9. (Article in German) 10.1007/BF00362223View ArticlePubMedGoogle Scholar
- Ulmer WT, Reichel G: Measurement of oxygen and carbon dioxide partial pressures in arterial and ear-lobe capillary blood with fixed micro-electrodes. Med Thorac 1963, 20: 235–49. (Article in German)PubMedGoogle Scholar
- Podlesch I, Ulmer WT: Whole body plethysmography. Beitr Klin Erforsch Tuberk Lungenkr 1966,133(4):305–11. (Article in German) 10.1007/BF02120691View ArticlePubMedGoogle Scholar
- Ulmer WT, Hoffarth HP: Whole body plethysmography for determining intrathoracic gas volume. Pneumologie 1993,47(10):579–82. (Article in German)PubMedGoogle Scholar
- Ulmer WT: Modern diagnosis of pulmonary function. Med Welt 1977,28(15):710–5. (Article in German)PubMedGoogle Scholar
- Kowalski J, Ulmer WT: Airway obstruction, emphysema and volumen pulmonum auctum. Verh Dtsch Ges Inn Med 1977, 83: 1472–4. (Article in German)PubMedGoogle Scholar
- Ulmer WT, Baving G, Reichel G: Physiopathological considerations in the treatment of coal workers' pneumoconiosis. Ann NY Acad Sci 1972, 200: 633–42. 10.1111/j.1749-6632.1972.tb40222.xView ArticlePubMedGoogle Scholar
- Ulmer WT, Reichel G: Functional impairment in coal workers' pneumoconiosis. Ann NY Acad Sci 1972, 200: 405–12. 10.1111/j.1749-6632.1972.tb40205.xView ArticlePubMedGoogle Scholar
- Gillissen A, Höltmann B, Schött D, Ulmer WT: Static compliance in subjects with intact lungs. Respiration 1989,55(3):176–80. 10.1159/000195729View ArticlePubMedGoogle Scholar
- Rasche K, Hoffarth HP, Ulmer WT: Functional disorders in obstructive respiratory tract diseases. Verh Dtsch Ges Inn Med 1990, 96: 58–65. (Article in German) 10.1007/978-3-642-84317-4_13PubMedGoogle Scholar
- Ulmer WT: Lung function disturbances caused by industrial lung disease. Ind Med Surg 1964, 33: 44–51.PubMedGoogle Scholar
- Ulmer WT, Reichel G, Werner U: Chronic obstructive bronchitis of the coal miner. An epidemiologic study of its incidence in the normal population and in coal miners. The importance of dust and smoking. Int Arch Arbeitsmed 1968,25(1):75–98. (Article in German)PubMedGoogle Scholar
- Ulmer WT: Silicosis. Pathophysiology and clinical aspects. Med Klin 1971,66(9):293–7. (Article in German)PubMedGoogle Scholar
- Ulmer WT: Inhalation therapy with atropine derivatives. Med Klin 1971,66(9):326–9. (Article in German)PubMedGoogle Scholar
- Ulmer WT, Höltmann B, Schmidt EW, Schött D: Anticholinergics as bronchodilators. An action profile. Arzneimittelforschung 1987,37(10):1185–92. (Article in German)PubMedGoogle Scholar
- Staguhn M, Kowalski J, Höltmann B, Ulmer WT: Obstructive airway diseases and cigarette smoking. Dtsch Med Wochenschr 1986,111(11):405–10. (Article in German) 10.1055/s-2008-1068464View ArticlePubMedGoogle Scholar
- Tomaszewski JJ, Hanzlik J, Wozniak K, Donica H, Kozak J, Szarugiewicz-Portala A, Spiewak B, Ulmer WT: Some risk factors of coronary heart disease in miners of a new coal mining area. Pol J Occup Med 1988,1(4):278–85.PubMedGoogle Scholar
- Ulmer WT: Lung function-clinical importance, problems, and new results. J Physiol Pharmacol 2003,54(Suppl 1):11–3.PubMedGoogle Scholar
- Ulmer WT, Schäfer T: New insights into physiology and pathophysiology by resistance-volume recordings. J Physiol Pharmacol 2004,55(Suppl 3):149–53.PubMedGoogle Scholar