From: Relationship between GNAS1 T393C polymorphism and aseptic loosening after total hip arthroplasty
All | GNAS1 T393C genotype | p value | |||
---|---|---|---|---|---|
TT | TC | CC | |||
Primary THA | |||||
n (%) | 231 | 52 (22.5) | 122 (52.8) | 57 (24.7) | |
Age at implantation (years) | 64.54 ± 10.9 | 62.12 ± 11.3 | 65.77 ± 10.0 | 64.12 ± 12.0 | 0.136 |
Gender | |||||
Female (%) | 151 (65.4) | 39 (25.8) | 80 (53.0) | 32 (21.2) | 0.118 |
Male (%) | 80 (34.6) | 13 (16.3) | 42 (52.5) | 25 (31.3) | |
BMI (kg/m2) | 27.31 ± 4.5 | 26.95 ± 4.6 | 27.64 ± 4.3 | 27.00 ± 4.9 | 0.556 |
Aseptic loosening | |||||
n (%) | 234 | 44 (18.8) | 126 (53.8) | 64 (27.4) | |
Age at implantation (years) | 52.80 ± 12.8 | 51.44 ± 13.6 | 53.08 ± 13.1 | 53.22 ± 11.6 | 0.735 |
Age at replantation (years) | 65.34 ± 12.4 | 63.20 ± 12.6 | 65.53 ± 12.7 | 66.46 ± 11.9 | 0.399 |
Gender | |||||
Female (%) | 165 (70.5) | 31 (18.8) | 87 (52.7) | 47 (28.5) | 0.821 |
Male (%) | 69 (29.5) | 13 (18.8) | 39 (56.5) | 17 (24.6) | |
BMI (kg/m2) | 26.94 ± 5.9 | 27.15 ± 4.8 | 27.13 ± 7.0 | 26.45 ± 3.9 | 0.734 |
First cup with cement (n = 212) | |||||
No | 73 (34.4) | 15 (20.5) | 37 (50.7) | 21 (28.8) | 0.749 |
Yes | 139 (65.6) | 26 (18.7) | 78 (56.1) | 35 (25.2) | |
First stem with cement (n = 213) | |||||
No | 75 (35.2) | 14 (18.7) | 42 (56.0) | 19 (25.3) | 0.946 |
Yes | 138 (64.8) | 27 (19.6) | 74 (53.6) | 37 (26.8) |