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Table 1 Clinical characteristics and genotype distribution in patients with primary THA and patients with aseptic loosening

From: Relationship between GNAS1 T393C polymorphism and aseptic loosening after total hip arthroplasty

 

All

GNAS1 T393C genotype

p value

TT

TC

CC

Primary THA

 n (%)

231

52 (22.5)

122 (52.8)

57 (24.7)

 

 Age at implantation (years)

64.54 ± 10.9

62.12 ± 11.3

65.77 ± 10.0

64.12 ± 12.0

0.136

Gender

 Female (%)

151 (65.4)

39 (25.8)

80 (53.0)

32 (21.2)

0.118

 Male (%)

80 (34.6)

13 (16.3)

42 (52.5)

25 (31.3)

 BMI (kg/m2)

27.31 ± 4.5

26.95 ± 4.6

27.64 ± 4.3

27.00 ± 4.9

0.556

Aseptic loosening

 n (%)

234

44 (18.8)

126 (53.8)

64 (27.4)

 

 Age at implantation (years)

52.80 ± 12.8

51.44 ± 13.6

53.08 ± 13.1

53.22 ± 11.6

0.735

 Age at replantation (years)

65.34 ± 12.4

63.20 ± 12.6

65.53 ± 12.7

66.46 ± 11.9

0.399

Gender

 Female (%)

165 (70.5)

31 (18.8)

87 (52.7)

47 (28.5)

0.821

 Male (%)

69 (29.5)

13 (18.8)

39 (56.5)

17 (24.6)

 BMI (kg/m2)

26.94 ± 5.9

27.15 ± 4.8

27.13 ± 7.0

26.45 ± 3.9

0.734

First cup with cement (n = 212)

 No

73 (34.4)

15 (20.5)

37 (50.7)

21 (28.8)

0.749

 Yes

139 (65.6)

26 (18.7)

78 (56.1)

35 (25.2)

First stem with cement (n = 213)

 No

75 (35.2)

14 (18.7)

42 (56.0)

19 (25.3)

0.946

 Yes

138 (64.8)

27 (19.6)

74 (53.6)

37 (26.8)

  1. Data are numbers with percentages given in brackets and numbers with standard deviation, respectively. Categorical variables were analyzed by χ 2 statistics. p values were calculated using ANOVA for continuous variables