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Table 1 Clinical characteristics and genotype distribution in patients with primary THA and patients with aseptic loosening

From: Relationship between GNAS1 T393C polymorphism and aseptic loosening after total hip arthroplasty

  All GNAS1 T393C genotype p value
TT TC CC
Primary THA
 n (%) 231 52 (22.5) 122 (52.8) 57 (24.7)  
 Age at implantation (years) 64.54 ± 10.9 62.12 ± 11.3 65.77 ± 10.0 64.12 ± 12.0 0.136
Gender
 Female (%) 151 (65.4) 39 (25.8) 80 (53.0) 32 (21.2) 0.118
 Male (%) 80 (34.6) 13 (16.3) 42 (52.5) 25 (31.3)
 BMI (kg/m2) 27.31 ± 4.5 26.95 ± 4.6 27.64 ± 4.3 27.00 ± 4.9 0.556
Aseptic loosening
 n (%) 234 44 (18.8) 126 (53.8) 64 (27.4)  
 Age at implantation (years) 52.80 ± 12.8 51.44 ± 13.6 53.08 ± 13.1 53.22 ± 11.6 0.735
 Age at replantation (years) 65.34 ± 12.4 63.20 ± 12.6 65.53 ± 12.7 66.46 ± 11.9 0.399
Gender
 Female (%) 165 (70.5) 31 (18.8) 87 (52.7) 47 (28.5) 0.821
 Male (%) 69 (29.5) 13 (18.8) 39 (56.5) 17 (24.6)
 BMI (kg/m2) 26.94 ± 5.9 27.15 ± 4.8 27.13 ± 7.0 26.45 ± 3.9 0.734
First cup with cement (n = 212)
 No 73 (34.4) 15 (20.5) 37 (50.7) 21 (28.8) 0.749
 Yes 139 (65.6) 26 (18.7) 78 (56.1) 35 (25.2)
First stem with cement (n = 213)
 No 75 (35.2) 14 (18.7) 42 (56.0) 19 (25.3) 0.946
 Yes 138 (64.8) 27 (19.6) 74 (53.6) 37 (26.8)
  1. Data are numbers with percentages given in brackets and numbers with standard deviation, respectively. Categorical variables were analyzed by χ 2 statistics. p values were calculated using ANOVA for continuous variables