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Table 3 Changes in inflammatory factors after initiation of roxadustat

From: Roxadustat alleviates the inflammatory status in patients receiving maintenance hemodialysis with erythropoiesis-stimulating agent resistance by increasing the short-chain fatty acids producing gut bacteria

Time

IL-1 (ng/L)

IL-6 (ng/L)

TNF-α (ng/L)

IFN-γ (ng/L)

ET (ng/L)

Baseline (M0)

107.72 ± 17.54

36.54 ± 5.84

55.13 ± 10.58

52.28 ± 8.94

7.82 ± 1.94

M1

85.13 ± 15.97

30.05 ± 5.41

44.14 ± 10.02

37.15 ± 9.11

6.11 ± 1.72

M3

73.75 ± 16.26

28.84 ± 5.68

42.97 ± 9.93

35.42 ± 8.70

5.54 ± 1.55

F value

603.626

271.113

321.807

906.224

493.483

P value

< 0.001

< 0.001

< 0.001

< 0.001

< 0.001

  1. M0: before roxadustat; M1: 1 month after initiation of roxadustat; M3: 3 months after initiation of roxadustat (end of study)
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European Journal of Medical Research

ISSN: 2047-783X

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