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Table 3 Exemplary characterization of two maxima of peaks in both lung and throat samples

From: Rapid point-of-care detection of SARS-CoV-2 infection in exhaled breath using ion mobility spectrometry: a pilot study

 

Site

SARS-CoV-2 PCR negative

SARS-CoV-2 PCR positive

AROC (CI)

pU (result)

Mean (SD)

Median (Q1 … Q3)

Mean (SD)

Median (Q1 … Q3)

Peak 1-lung

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TUM

17.57 (11.46)

14.72 (10.11 … 21.31)

13.21 (8.73)

11.59 (8.13 … 15.20)

0.357 (0.296 … 0.418)

< 0.001

CBF

17.32 (8.08)

16.14 (11.48 … 21.80)

12.56 (4.94)

10.65 (8.43 … 16.98)

0.306 (0.183 … 0.428)

0.005

pU (site)

0.521

0.728

  

Peak 1-throat

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TUM

18.04 (11.32)

14.55 (11.12 … 21.07)

14.08 (9.88)

11.42 (8.55 … 15.07)

0.346 (0.285 … 0.407)

< 0.001

CBF

19.10 (10.96)

15.97 (11.74 … 21.65)

13.66 (6.51)

13.50 (8.70 … 15.22)

0.323 (0.198 … 0.447)

0.010

pU (site)

0.371

0.365

  

Peak 2-lung

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TUM

9.75 (9.41)

8.70 (6.30 … 11.01)

8.66 (9.25)

7.14 (5.48 … 9.24)

0.374 (0.312 … 0.436)

< 0.001

CBF

6.85 (3.83)

5.83 (4.75 … 7.62)

5.31 (2.10)

4.67 (4.02 … 6.56)

0.335 (0.207 … 0.462)

0.017

pU (site)

< 0.001

< 0.001

  

Peak 2-throat

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TUM

16.23 (19.42)

12.82 (8.97 … 19.09)

12.15 (9.43)

9.88 (7.12 … 14.92)

0.381 (0.318 … 0.443)

< 0.001

CBF

7.40 (3.77)

6.29 (5.09 … 8.29)

5.85 (1.69)

5.76 (4.47 … 6.84)

0.379 (0.248 … 0.509)

0.080

pU (site)

< 0.001

< 0.001

  
  1. The bar graphs on the left show the distribution of peak intensities in quartiles (red, dark blue: Q2; yellow, light blue: Q3). The x-axis signal intensity is expressed in arbitrary units (\(\times {10}^{3}\)). The table on the right shows the statistical characteristics of the peaks. Statistical significance was assessed using the Mann–Whitney U test
  2. TUM, Technical University of Munich; CBF, Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin; SD, standard deviation; Q1–4, quartile 1–4; CI, confidence interval