Fig. 4

Analysis of marker genes and pseudo-time trajectory analysis of the common cells. A Robust DEMGs analysis in cell clusters of neurons, epithelial cells and smooth muscle cells by cross-tabulation. B Different cells in the GSE86469 dataset were ordered along trajectories to construct a pseudo-time axis. The darker the color, the earlier the cell progression begins. C Cell annotations in trajectory analysis. D Distribution of 5 sub-clusters in trajectory. E Distribution of non-diabetic or T2DM sample cells in trajectory