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  1. Chronic renal failure (CRF) is a progressive loss of renal function that lead to reduced sodium filtration and inappropriate suppression of tubular reabsorption that ultimately leads to volume expansion. The a...

    Authors: Moustafa Mahmoud Hamdy, Mahran S. Abdel-Rahman, Dalia M. Badary and Mahmoud S. Sabra
    Citation: European Journal of Medical Research 2022 27:117
  2. Intrahepatic cholangiocarcinoma (ICC), highly invasive and highly heterogeneous, has a poor prognosis. It has been confirmed that many risk factors are associated with ICC including intrahepatic lithiasis, pri...

    Authors: Yinghui Song, Mengting Cai, Yuhang Li and Sulai Liu
    Citation: European Journal of Medical Research 2022 27:116

    The Correction to this article has been published in European Journal of Medical Research 2022 27:166

  3. Exostosin like glycosyltransferase 3 (EXTL3) had been reported to be associated with immune deficiency and play prognostic roles in various cancers. However, little is known about the associations between EXTL...

    Authors: Pingan Chang, Shenglan Chen, Xiumei Chang, Jiaxi Zhu, Qingsheng Tang and Limin Ma
    Citation: European Journal of Medical Research 2022 27:115
  4. Thyroid hormones play an instrumental role in chondrogenic differentiation and matrix maturation. However, studies investigating the relationship between thyroid function and the risk of osteoarthritis (OA) re...

    Authors: Shuai Chen, Xiaohe Sun, Guowei Zhou, Jie Jin and Zhiwei Li
    Citation: European Journal of Medical Research 2022 27:114
  5. The placental examination provides important information about the effect of maternal abnormalities on the placenta or the cause of preterm delivery, fetal growth restriction, or fetal neurodevelopmental damag...

    Authors: Setareh Akhavan, Sedigheh Borna, Alireza Abdollahi, Mamak Shariat and Narges Zamani
    Citation: European Journal of Medical Research 2022 27:113
  6. Abnormal vitamin D is prevalent in critical care settings, but its association with prognosis remains unclear. The study aimed to investigate the prevalence and predictors of abnormal blood 25-hydroxyvitamin D...

    Authors: Juntao Xie, Qingui Chen and Dejian He
    Citation: European Journal of Medical Research 2022 27:111
  7. This study aimed to investigate the effect of conventional drugs combined with acupuncture therapy on the conversion of sinus rhythm in patients with atrial fibrillation.

    Authors: Yibing Li, Jinming Song, Bangqi Wu, Xuhui Wang, Lin Han and Zhenzhen Han
    Citation: European Journal of Medical Research 2022 27:110
  8. Based on the social-ecological model, this study aimed to comprehensively explore factors affecting the risk of ischemic cerebrovascular disease (ICVD) in postmenopausal women to provide theoretical bases for ...

    Authors: Chun-Jun Yang, Dong-Mei Wang, Tong Wang and Ying Song
    Citation: European Journal of Medical Research 2022 27:109
  9. Bacteria associated with dental caries have a high ability to produce organic acids from dietary carbohydrates during growth and metabolism under acidic conditions. In contrast, many symbiotic bacteria produce...

    Authors: Samaneh Vaziriamjad, Mobina Solgi, Farideh Kamarehei, Fatemeh Nouri and Mohammad Taheri
    Citation: European Journal of Medical Research 2022 27:108
  10. Glutamate signaling activates MAPK and PI3K/AKT pathways in tumor cells. Treatment with riluzole, a glutamate release inhibitor, has been previously shown to be safe in melanoma patients and produced biologic ...

    Authors: Ann W. Silk, Biren Saraiya, Roman Groisberg, Nancy Chan, Kristen Spencer, Eugenia Girda, Weichung Shih, Marisa Palmeri, Tracie Saunders, Robert M. Berman, Vlad Coric, Suzie Chen, Andrew Zloza, Joshua Vieth, Janice M. Mehnert and Jyoti Malhotra
    Citation: European Journal of Medical Research 2022 27:107
  11. Chronic inflammatory disorders in atrial fibrillation (AF) contribute to the onset of ischemic stroke. Systemic immune inflammation index (SIII) and system inflammation response index (SIRI) are the two novel ...

    Authors: Kai-bin Lin, Feng-hua Fan, Ming-qi Cai, Yin Yu, Chuan-liang Fu, Lu-yue Ding, Yu-dong Sun, Jia-wen Sun, Yong-wang Shi, Zhi-feng Dong, Min-Jie Yuan, Shuai Li, Yan-peng Wang, Kan-kai Chen, Ji-ni Zhu, Xin-wei Guo…
    Citation: European Journal of Medical Research 2022 27:106
  12. Androgen deprivation therapy (ADT) is still the first-line treatment of prostate cancer (PCa). However, after a certain period of therapy, primary PCa inevitably progresses into castration-resistant PCa (CRPC)...

    Authors: Xi Chen, Yechen Wu, Xinan Wang, Chengdang Xu, Licheng Wang, Jingang Jian, Denglong Wu and Gang Wu
    Citation: European Journal of Medical Research 2022 27:105
  13. Bone biopsies are often necessary to make a diagnosis in the case of irregular bone structures of the jaw. A 3D-printed surgical guide may be a helpful tool for enhancing the accuracy of the biopsy and for ens...

    Authors: Lukas Postl, Thomas Mücke, Stefan Hunger, Sabina Noreen Wuersching, Svenia Holberg, Oliver Bissinger, Rainer Burgkart, Michael Malek and Stefan Krennmair
    Citation: European Journal of Medical Research 2022 27:104
  14. The objective of the study was to demonstrate the cortical thickness character in the humeral surgical neck region using 3D cortical bone mapping technique and try to illustrate its morphological changes with ...

    Authors: Jialiang Guo, Yali Zhou, Meishuang Shang, Wei Chen, Zhiyong Hou, Yingze Zhang and Weichong Dong
    Citation: European Journal of Medical Research 2022 27:102
  15. The connection between initial viral cycle threshold (Ct) values of the SARS-CoV-2 with symptoms and hospital course is not clearly studied.

    Authors: Salma AlBahrani, Mohammed Alghamdi, Nawaf Zakary, Arulanantham Zechariah Jebakumar, Samirah Jamaan AlZahrani, Mohamed Hany ElGezery, Khaled Omar Abdallah and Jaffar A. Al-Tawfiq
    Citation: European Journal of Medical Research 2022 27:101
  16. Leiomyosarcoma originating from the renal vein (RVLMS) is extremely rare. RVLMS lacks specific clinical manifestations and specific imaging features. This article discusses the epidemiological characteristics ...

    Authors: Qais Baheen, Hai Bi, Kai Wang, Min Lu, Hongxian Zhang and Lulin Ma
    Citation: European Journal of Medical Research 2022 27:100
  17. Pancreatic calcifications (PC) are considered specific for chronic pancreatitis (CP), but PC may also be present in non-CP diseases. The aims are to understand the pattern of calcifications in different diseas...

    Authors: Wei Wang, Li Chai, Naiyi Zhu, Qingrou Wang, Yiran Zhou and Weimin Chai
    Citation: European Journal of Medical Research 2022 27:99
  18. Antibiotic resistance is a major global public health problem. The primary cause of antibiotic resistance is inappropriate antibiotic use. In this study, we aimed to verify whether the monthly evaluation of an...

    Authors: Qiong Yang, Fangfang Yuan, Li Li, Jianfeng Jin and Junhong He
    Citation: European Journal of Medical Research 2022 27:98
  19. The influence of immunosuppressive therapy on immunogenicity after COVID-19 vaccination remains unclear. This study surveys patients who receive immunosuppressive therapy about whether or not they paused their...

    Authors: Dominik Schröder, Stephanie Heinemann, Gloria Heesen, Frank Klawonn, Marie Mikuteit, Jacqueline Niewolik, Sandra Steffens, Georg Behrens, Alexandra Jablonka and Frank Müller
    Citation: European Journal of Medical Research 2022 27:97
  20. Neuromyelitis optica spectrum disorders (NMOSDs) are blindness-causing neuritis; their pathogenesis is still not fully elucidated. Although it has been determined that Bruton tyrosine kinase (BTK) and NF-κB ar...

    Authors: Huimin Qiao, Zhuofeng Mao, Wei Wang, Xin Chen, Suhuan Wang, Haolong Fan, Tianyi Zhao, Huiqing Hou and Mei Dong
    Citation: European Journal of Medical Research 2022 27:96
  21. Clinical research publications have become the dominant source and basis of clinical evidence-based decision-making. Exploring the type and quantity of clinical research publications in the PubMed database is ...

    Authors: Xiyi Zhao, Hao Jiang, Jianyun Yin, Hongchao Liu, Ruifang Zhu, Shencong Mei and Chang-tai Zhu
    Citation: European Journal of Medical Research 2022 27:95
  22. To describe, through a literature review, the results and benefits of oral and topical probiotics for adult patients with atopic dermatitis.

    Authors: Camila Stofella Sodré, Mayra Stambovsky Vieira, Juliany Lima Estefan, Cristiane Moraes, Fernanda Sampaio Cavalcante, Kátia Regina Netto dos Santos and Dennis de Carvalho Ferreira
    Citation: European Journal of Medical Research 2022 27:94
  23. Alzheimer’s disease (AD) as a neurodegenerative disease occupies 3/5–4/5 cases among patients with dementia, yet its pathogenetic mechanism remains unclear. Geraniol, on the other hand, is a well-known extract...

    Authors: Ying Liu, Shujing Zhou, Xufeng Huang and Hafiz Muzzammel Rehman
    Citation: European Journal of Medical Research 2022 27:93
  24. Endocrine orbitopathy is typically treated by resecting orbital walls. This procedure reduces intraorbital pressure by releasing intraorbital tissue, effectively alleviating the symptoms. However, selection of...

    Authors: Matthias Krause, Michael-Tobias Neuhaus, Ina Sterker, Alexander K. Bartella, Annika Schönfeld, Bernd Lethaus, Rüdiger Zimmerer and Evgeny Gladilin
    Citation: European Journal of Medical Research 2022 27:92
  25. Obesity is very common in patients with schizophrenia. We aimed to evaluate the influencing factors of obesity in community patients with deficit schizophrenia, to provide implication for schizophrenia managem...

    Authors: Na Yong, Jiyang Pan, Xuehua Li, Ling Yu and Xin Hou
    Citation: European Journal of Medical Research 2022 27:90
  26. Malignancy-related hypercalcemia is a leading cause of hypercalcemia among hospitalized patients that carries poor prognosis. Parathyroid carcinoma is a rare form of primary hyperparathyroidism that may be ass...

    Authors: Marc Scheen, Grzegorz Nowak, Bienvenido Sanchez and Daniel Teta
    Citation: European Journal of Medical Research 2022 27:89
  27. Currently, there are relatively few studies on the effects of changes in oestrogen and androgen levels on prostatic microvessel density (MVD). This article aimed to study the changes in prostatic MVD in Spragu...

    Authors: Bo Wang, Di Pan, Yong Ban, Zhaolin Sun, Ye Tian and Guangheng Luo
    Citation: European Journal of Medical Research 2022 27:87
  28. To locate an anastomosable constant perforator of the radial artery on the proximal forearm using ultrasonography and describe the application of a free radial artery flap based on a single proximal perforator...

    Authors: Guangzhi Wu, Zhan Zhang, Fan Zhang, Yiqun Zhang, Qianqian Wang and Wei Yu
    Citation: European Journal of Medical Research 2022 27:85
  29. During the last 2 years, in the Kurdistan Region, Northern Iraq, there were thousands of COVID-19 cases that have not been reported officially, but diagnosed and confirmed by private laboratories and private h...

    Authors: Hemn Muhammed Mustafa, Darya Saeed Abdulateef and Heshu Sulaiman Rahman
    Citation: European Journal of Medical Research 2022 27:84
  30. C-reactive protein (CRP) is an important biomarker of inflammation and plays a pivotal role in predicting the clinical prognosis of cardiovascular and cerebrovascular diseases. However, the mechanism of inflam...

    Authors: Tan Li, Qiannan Yu, Yiqing Wang, Xiuying Cai, Yan Kong, Hongru Zhao, Shanshan Diao, Yiren Qin and Qi Fang
    Citation: European Journal of Medical Research 2022 27:83
  31. Covid-19 has been one of the major concerns around the world in the last 2 years. One of the challenges of this disease has been to determine its prevalence. Conflicting results of the serology test in Covid e...

    Authors: Mobin Azami, Yousef Moradi, Asra Moradkhani and Abbas Aghaei
    Citation: European Journal of Medical Research 2022 27:81
  32. Vaccination against SARS-CoV-2 has been the main tool to contain the pandemic. The rush development of the 3 vaccines and their expedited approval have led to inoculation of millions of patients around the wor...

    Authors: Noemi F. Freise, Milena Kivel, Olaf Grebe, Christian Meyer, Bahram Wafaisade, Matthias Peiper, Tobias Zeus, Jan Schmidt, Judith Neuwahl, Danny Jazmati, Tom Luedde, Edwin Bölke, Torsten Feldt, Björn Erik Ole Jensen, Johannes Bode, Verena Keitel…
    Citation: European Journal of Medical Research 2022 27:80
  33. Acute lung injury (ALI) caused by intestinal ischemia–reperfusion is a life-threatening disease. Interferon gene stimulator (STING) is a cytoplasmic DNA sensor that participates in the initiation of the inflammat...

    Authors: Mei Yang, Yu-Xia Ma, Ying Zhi, Hai-Bin Wang, Li Zhao, Peng-Sheng Wang and Jie-Ting Niu
    Citation: European Journal of Medical Research 2022 27:79
  34. Extracorporeal membrane oxygenation (ECMO) to support cardiopulmonary resuscitation (CPR), also known as extracorporeal cardiopulmonary resuscitation (ECPR), has shown encouraging results in refractory cardiac...

    Authors: Linhui Hu, Kaiyi Peng, Xiangwei Huang, Zheng Wang, Yuyu Wu, Hengling Zhu, Jingyao Ma and Chunbo Chen
    Citation: European Journal of Medical Research 2022 27:77
  35. Tendon injuries are widespread and chronic disorders of the musculoskeletal system, frequently caused by overload of the tendons. Currently, the most common treatment for tendon injuries is "cell-free therapy"...

    Authors: Kexin Lyu, Tianzhu Liu, Yixuan Chen, Jingwei Lu, Li Jiang, Xueli Liu, Xinyue Liu, Yujie Li and Sen Li
    Citation: European Journal of Medical Research 2022 27:75
  36. In hepatocellular carcinoma (HCC) patients, intraarterial therapies are regularly employed as a bridge to liver transplantation to prevent tumor progression during waiting time. Objective of this study was to ...

    Authors: Tamás Benkö, Julia König, Jens M. Theysohn, Clemens Schotten, Fuat H. Saner, Jürgen Treckmann and Sonia Radunz
    Citation: European Journal of Medical Research 2022 27:74
  37. Stroke is a type of cerebrovascular disease that significantly endangers human health and lowers quality of life. This understandably places a heavy burden on society and families. In recent years, intestinal ...

    Authors: Wenjie Hu, Xiangyi Kong, Hui Wang, Yunqing Li and Yimin Luo
    Citation: European Journal of Medical Research 2022 27:73
  38. As one of the most common primary headaches in clinical practice, migraine affects the learning ability and life quality of college students worldwide, posing a heavy burden on individuals and society. This st...

    Authors: Haodi Yang, Shengxiong Pu, Yang Lu, Wenxiu Luo, Jiayu Zhao, Enzhuo Liu, Jiaming Yang, Xinya Luo, Xinyi Tang, Cheng Zeng, Jie Chen and Jiaming Luo
    Citation: European Journal of Medical Research 2022 27:71
  39. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the agent of a pneumonia outbreak and was called 2019 novel coronavirus disease (COVID-19). COVID-19 emerged in December 2019 and now considered ...

    Authors: Seyed-Amir Tabatabaeizadeh
    Citation: European Journal of Medical Research 2022 27:70
  40. Serum Krebs von den Lungen 6 (KL-6), which reflects alveolar epithelial injury, was reported to be useful to predict the progression of pneumonitis induced by COVID-19 in the early phase. This study aimed to e...

    Authors: Shuhei Maruyama, Yasushi Nakamori, Hitoshi Nakano, Keiko Tsuyumu, Shuji Kanayama, Hiromu Iwamura, Daiki Wada, Tomoyuki Yoshihara, Fukuki Saito, Kazuhisa Yoshiya and Yasuyuki Kuwagata
    Citation: European Journal of Medical Research 2022 27:69

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