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  1. Intervertebral disc (IVD) cells experience a broad range of physicochemical stimuli under physiologic conditions, including alterations in their osmotic environment. At present, the molecular mechanisms underl...

    Authors: Wenzhi Zhang, Xu Li, Xifu Shang, Qichun Zhao, Yefeng Hu, Xiang Xu, Rui He, Liqun Duan and Feng Zhang
    Citation: European Journal of Medical Research 2013 18:62

    The Retraction Note to this article has been published in European Journal of Medical Research 2015 20:32

  2. Tumor-derived exosomes have been viewed as a source of tumor antigens that can be used to induce anti-tumor immune responses. In the current study, we aim to investigate the regulatory effect of the epigenetic...

    Authors: Wenhua Xiao, Weiwei Dong, Caihong Zhang, Gaowa Saren, Paili Geng, Huixia Zhao, Quiwen Li, Jianhua Zhu, Guanghui Li, Shufang Zhang and Ming Ye
    Citation: European Journal of Medical Research 2013 18:61
  3. Dopamine agonists (DA) are the first-choice drug for treatment of the early stage of Parkinson’s disease (PD) in subjects younger than 70 years. Recently, a number of third generation DA have been marketed, in...

    Authors: Clelia Pellicano, Dario Benincasa, Alessandra Fanciulli, Pamela Latino, Morena Giovannelli and Francesco E Pontieri
    Citation: European Journal of Medical Research 2013 18:60
  4. Hepatocellular carcinoma (HCC) is the fifth most common malignant tumor in men and the seventh in women and understanding the molecular mechanisms of HCC and establishing more effective therapies are critical ...

    Authors: Qin Wang, Jun Zhou, Dewu Zhong, Qunwei Wang and Jiangsheng Huang
    Citation: European Journal of Medical Research 2013 18:59

    The Retraction Note to this article has been published in European Journal of Medical Research 2015 20:38

  5. Acute lung injury (ALI) is a serious clinical syndrome with a high rate of mortality. In this study, the effects of triptolide on lipopolysaccharide (LPS)-induced ALI in rats were investigated.

    Authors: Jianling Gao, Ying Zhan, Jun Chen, Lina Wang and Jianping Yang
    Citation: European Journal of Medical Research 2013 18:58

    The Retraction Note to this article has been published in European Journal of Medical Research 2015 20:35

  6. The aim of this study was to establish an osteosarcoma (OS) associated protein-protein interaction network and explore the pathogenesis of osteosarcoma.

    Authors: Bi-Yong Deng, Ying-Qi Hua and Zheng-Dong Cai
    Citation: European Journal of Medical Research 2013 18:57

    The Retraction Note to this article has been published in European Journal of Medical Research 2015 20:40

  7. Prostate stem cell antigen (PSCA) is upregulated in prostate cancer tissues. Here we aimed to study the therapeutic efficacy of a monoclonal antibody of PSCA-labeled I131 (I131-PSCA-mAb) in orthotopic mouse model...

    Authors: Shengqiang Yu, Fan Feng, Ke Wang, Changping Men, Chunhua Lin, Qingzuo Liu, Diandong Yang and Zhenli Gao
    Citation: European Journal of Medical Research 2013 18:56
  8. In our study, we used meta-analysis to study the efficacy of the tourniquet on ankle trauma surgery. Postoperative infection rate, deep venous thrombosis incidence, hospital stay, and joint range of motion wer...

    Authors: Xinhua Jiang, Baoqing Yu, Wei Qu and Jiawen He
    Citation: European Journal of Medical Research 2013 18:55

    The Retraction Note to this article has been published in European Journal of Medical Research 2015 20:34

  9. Nonalcoholic fatty liver disease (NAFLD) is a risk for hepatocellular carcinoma (HCC), but the association between a high-fructose diet and HCC is not fully understood. In this study, we investigated whether a...

    Authors: Ryo Kumamoto, Hirofumi Uto, Kohei Oda, Rie Ibusuki, Shirou Tanoue, Shiho Arima, Seiichi Mawatari, Kotaro Kumagai, Masatsugu Numata, Tsutomu Tamai, Akihiro Moriuchi, Hiroshi Fujita, Makoto Oketani, Akio Ido and Hirohito Tsubouchi
    Citation: European Journal of Medical Research 2013 18:54
  10. To study the efficacy and safety of cilostazol on ischemic stroke prevention and treatment, systematic reviews of related clinical randomized controlled trials were analyzed.

    Authors: Yining Qian and Qi Bi
    Citation: European Journal of Medical Research 2013 18:53

    The Retraction Note to this article has been published in European Journal of Medical Research 2015 20:39

  11. Increased metastasis has been proved to be associated with a poor prognosis for hepatocellular carcinoma (HCC). There are higher-level expressions of integrin α6 in the tissues of HCC patients with a higher fa...

    Authors: Guannan Lv, Tianjing Lv, Shifeng Qiao, Wei Li, Weiran Gao, Xiaohui Zhao and Jikun Wang
    Citation: European Journal of Medical Research 2013 18:52
  12. The main purpose of this study was to assess the feasibility and relevant applying techniques of total thyroidectomy for thyroid carcinoma with a modified Miccoli’s approach.

    Authors: Xiang Shen, Zhi-ming Miao, Wei Lu, Da-li Gu, Dan Yang, Hao Shen and Feng Geng
    Citation: European Journal of Medical Research 2013 18:51
  13. Several studies demonstrated acute inflammatory response following traumatic injury. Inflammatory response during surgical interventions was verified by a significant increase of endotoxin plasma levels and a ...

    Authors: Klaus Orth, Wolfram Trudo Knoefel, Martijn van Griensven, Christiane Matuschek, Matthias Peiper, Holger Schrumpf, Peter Arne Gerber, Wilfried Budach, Edwin Bölke, Bettina Alexandra Buhren and Matthias Schauer
    Citation: European Journal of Medical Research 2013 18:50
  14. The efficacy of highly active antiretroviral therapy (HAART) in the treatment of HIV infection is influenced by factors such as potency of applied drugs, adherence of the patient, and resistance-associated mut...

    Authors: Mark Oette, Stefan Reuter, Rolf Kaiser, Björn Jensen, Thomas Lengauer, Gerd Fätkenheuer, Heribert Knechten, Martin Hower, Abdurrahman Sagir, Herbert Pfister and Dieter Häussinger
    Citation: European Journal of Medical Research 2013 18:48
  15. The aim of this study is to investigate the effects of polyphenol extract from Phyllanthus emblica (PEEP) on cervical cancer cells and to explore the underlying mechanism.

    Authors: Xinxian Zhu, Jianjun Wang, Yang Ou, Weiwei Han and Huaifang Li
    Citation: European Journal of Medical Research 2013 18:46
  16. Post-transplant anemia (PTA) has long been a less-recognized complication in kidney transplant recipients, and its prevalence also tends to be underestimated. This study sought to evaluate the prevalence, mana...

    Authors: Zhixian Wu, Junqi Guo, Lianming Liao, Weizhen Wu, Shunliang Yang and Jianming Tan
    Citation: European Journal of Medical Research 2013 18:45
  17. Primary hepatocellular carcinoma (HCC) is one of the most common malignancies in the world. However, the molecular pathogenesis of HCC is not well-understood, and the prognosis for patients with HCC remains ve...

    Authors: Deyong Kong, Heming Chen, Weiqun Chen, Shuiyi Liu, Hui Wang, Tangwei Wu, Hongda Lu, Qingzhi Kong, Xiaodong Huang and Zhongxin Lu
    Citation: European Journal of Medical Research 2013 18:44

    The Retraction Note to this article has been published in European Journal of Medical Research 2015 20:31

  18. Melasma is a common hypermelanosis of the face. The use of a classical Q-switched ruby laser (QSRL) to treat melasma is discussed controversially and is associated with frequent adverse effects, such as hyper-...

    Authors: Said Hilton, Heike Heise, Bettina Alexandra Buhren, Holger Schrumpf, Edwin Bölke and Peter Arne Gerber
    Citation: European Journal of Medical Research 2013 18:43
  19. Our purpose was to investigate the clinical efficacy of arthroscope-assisted acromioclavicular ligament reconstruction in combination with double endobutton coracoclavicular ligament reconstruction for the tre...

    Authors: Haoqing Li, Chuanshun Wang, Jiandong Wang, Kai Wu and Donghua Hang
    Citation: European Journal of Medical Research 2013 18:42
  20. miRNAs are a class of small non-coding RNA molecules that play an important role in the pathogenesis of human diseases through negative regulation of gene expression. Although miRNA-10b (miR-10b) has been impl...

    Authors: Yi Liu, Minghui Li, Guoqing Zhang and Zuoliang Pang
    Citation: European Journal of Medical Research 2013 18:41
  21. With an aging society and raised expectations, joint replacement surgery is likely to increase significantly in the future. The development of postoperative complications following joint replacement surgery (f...

    Authors: Stephen F Hughes, Beverly D Hendricks, David R Edwards, Salah S Bastawrous and Jim F Middleton
    Citation: European Journal of Medical Research 2013 18:40
  22. A 62 year-old patient with therapy-refractory pouchitis after proctocolectomy for ulcerative colitis was admitted with hematochezia and abdominal discomfort. A malignant melanoma (MM) was found after repeated ...

    Authors: Philipp Lingohr, Thomas Galetin, Hanno Matthaei, Eberhard Straub, Azin Jafari, Edwin Bölke, Jörg C Kalff and Karl-Heinz Vestweber
    Citation: European Journal of Medical Research 2013 18:39
  23. Multicentric reticulohistiocytosis (MRH) is a very rare systemic disease with variable phenotypic presentation and a high rate of misdiagnosis. Here we describe a patient with MRH and extra-mammillary Paget’s ...

    Authors: Xinyan Huang, Limei Zhang and Songzhao Zhang
    Citation: European Journal of Medical Research 2013 18:38
  24. The aim of this study was to identify key genes and novel potential therapeutic targets related to gastric cancer (GC) by comparing cancer tissue samples and healthy control samples using DNA microarray analysis.

    Authors: Yong Jin and Wei Da
    Citation: European Journal of Medical Research 2013 18:37

    The Retraction Note to this article has been published in European Journal of Medical Research 2015 20:30

  25. Prostate cancer (PCa) originating from the prostate base may intrude into the urinary bladder and may be misdiagnosed as bladder cancer. In this retrospective study, we reviewed the clinic data on PCa cases wh...

    Authors: Ranlu Liu, Xiaoqiang Xie, Zhihong Zhang and Yong Xu
    Citation: European Journal of Medical Research 2013 18:36
  26. Hepatocellular carcinoma (HCC) is one of the most common types of cancer worldwide. Despite several efforts to elucidate molecular mechanisms involved in this cancer, they are still not fully understood.

    Authors: Lingyan Zhang, Ying Guo, Bibo Li, Juan Qu, Chunbao Zang, Fang Li, Ying Wang, Hua Pang, Shaolin Li and Qingjun Liu
    Citation: European Journal of Medical Research 2013 18:35
  27. There are two completely contradictory views regarding the impact of human bone-marrow-derived mesenchymal stem cells (hMSCs) on hepatocellular carcinomas (HCCs). The aim of this study was to investigate the e...

    Authors: Tianran Li, Bin Song, Xiangke Du, Zhengmao Wei and Tianlong Huo
    Citation: European Journal of Medical Research 2013 18:34
  28. In recent years, many advances in pancreatic surgery have been achieved. Nevertheless, the rate of pancreatic fistula following pancreatic tail resection does not differ between various techniques, still reach...

    Authors: Aycan Akca, Peter E Goretzki, Denis Wirowski, Marc A Renter, Edwin Bölke, Christiane Matuschek, Peter Arne Gerber and Bernhard J Lammers
    Citation: European Journal of Medical Research 2013 18:33
  29. Thiamine deficiency has suggested to be linked to several insulin-resistance complications. In this study, we aim to associate circulating thiamine levels among cardiometabolic parameters in an Arab cohort usi...

    Authors: Nasser M Al-Daghri, Omar S Al-Attas, Khalid M Alkharfy, Majed S Alokail, Sherif H Abd-Alrahman and Shaun Sabico
    Citation: European Journal of Medical Research 2013 18:32
  30. With the Bonebridge, a new bone-anchored hearing aid has been available since March 2012. The objective of the study was to analyse the visualisation of the implant itself as well as its impact on the represen...

    Authors: Christian Güldner, Julia Heinrichs, Rainer Weiß, Annette Paula Zimmermann, Benjamin Dassinger, Siegfried Bien, Jochen Alfred Werner and Isabell Diogo
    Citation: European Journal of Medical Research 2013 18:30
  31. Cancer is the result of a complex multistep process that involves the accumulation of sequential alterations of several genes, including those encoding microRNAs (miRNAs) that have critical roles in the regula...

    Authors: Yahong Xu, Shunwen Luo, Yang Liu, Jian Li, Yi Lu, Zhigang Jia, Qihua Zhao, Xiaoping Ma, Minghui Yang, Yue Zhao, Ping Chen and Yu Guo
    Citation: European Journal of Medical Research 2013 18:29

    The Retraction Note to this article has been published in European Journal of Medical Research 2015 20:43

  32. It has been demonstrated that urokinase-type plasminogen activator (uPA) is involved in tumor cell metastasis by degrading the extracellular matrix. However, there is little direct evidence of clinical uPA sys...

    Authors: Youcheng Ding, Hui Zhang, Mingan Zhong, Zhuqing Zhou, Zhixiang Zhuang, Hua Yin, Xujing Wang and Zhenggang Zhu
    Citation: European Journal of Medical Research 2013 18:28
  33. An increase in serum uric acid (UA) occurs during the early and middle stages of chronic kidney disease (CKD) and aggravates the deterioration of kidney function. This study aims to explore the relation betwee...

    Authors: Yu Wang and Xiaorong Bao
    Citation: European Journal of Medical Research 2013 18:26

    The Retraction Note to this article has been published in European Journal of Medical Research 2015 20:44

  34. After more than 50 years of research, airway transplantation remains a major challenge in the fields of thoracic surgery and regenerative medicine. Five principal types of tracheobronchial substitutes, includi...

    Authors: Emmanuel Martinod, Agathe Seguin, Dana M Radu, Guillaume Boddaert, Kader Chouahnia, Anne Fialaire-Legendre, Hervé Dutau, Nicolas Vénissac, Charles-Hugo Marquette, Christophe Baillard, Dominique Valeyre and Alain Carpentier
    Citation: European Journal of Medical Research 2013 18:25
  35. Advances in endoscopy and anesthesia have enabled gastrointestinal endoscopy for children since 1960. Over the past decades, the number of endoscopies has increased rapidly. As specialized teams of pediatric g...

    Authors: Michael Friedt and Simon Welsch
    Citation: European Journal of Medical Research 2013 18:24
  36. Sonography has become the imaging technique of choice for guiding intraoperative interventions in abdominal surgery. Due to artefacts from residual air content, however, videothoracoscopic and open intraoperat...

    Authors: Thomas Günther Lesser, Harald Schubert, Sabine Bischoff and Frank Wolfram
    Citation: European Journal of Medical Research 2013 18:23
  37. The mammalian target of rapamycin inhibitors are normally favored as immunosuppressant agents for solid organ transplantation such as kidney, liver or heart. Only in recent years have they been increasingly ad...

    Authors: Gisela Schieren, Edwin Bölke, Axel Scherer, Andreas Raffel, Peter Arne Gerber, Patric Kröpil, Matthias Schott, Jackson Hamilton, Anne Hayman, Wolfram Trudo Knoefel, Wilfried Budach and Christiane Matuschek
    Citation: European Journal of Medical Research 2013 18:22
  38. Studies have demonstrated that autophagy pathways are activated in the brain after experimental subarachnoid hemorrhage (SAH) and this may play a protective role in early brain injury. However, the contributio...

    Authors: Yizhi Liu, Hongfa Cai, Zhong Wang, Jianke Li, Kaiyong Wang, Zhengquan Yu and Gang Chen
    Citation: European Journal of Medical Research 2013 18:21
  39. Postpartum vaginal cystic lesions constitute a common situation that is caused either by inflammation or by accumulation of lymph. We report a case of a 33-year-old woman who had bilateral duplication of the p...

    Authors: Nikolaos Machairiotis, Ioannis Tourountous, Alexandros Karamperis, Paul Zarogoulidis, Anastasia Oikonomou, Rokkos Theodoros, Panagiota Palouki, Wolfgang Hohenforst-Schmidt, Athanasios Zissimopoulos and Christodoulos Machairiotis
    Citation: European Journal of Medical Research 2013 18:20
  40. The cytokine growth differentiation factor-15 (GDF-15), a member of the TGF beta superfamily, has recently been discovered to play an important role in cardiovascular diseases. It is mostly expressed in macrop...

    Authors: Michael R Preusch, Matthias Baeuerle, Claudia Albrecht, Erwin Blessing, Marc Bischof, Hugo A Katus and Florian Bea
    Citation: European Journal of Medical Research 2013 18:19
  41. Human HIV-1 TAT interactive protein 2 (HTATIP2/TIP30) is an evolutionarily conserved gene that is expressed ubiquitously in human tissues and some tumor tissues. This protein has been found to be associated wi...

    Authors: Yakup Kumtepe, Zekai Halici, Ozlem Sengul, Celalettin Semih Kunak, Yasin Bayir, Nergiz Kilic, Elif Cadirci, Alparslan Pulur and Zafer Bayraktutan
    Citation: European Journal of Medical Research 2013 18:18
  42. A variety of pharmacological and surgical treatments have been developed for heavy menstrual bleeding (HMB), which can have negative physical, social, psychological, and economic consequences. We conducted a s...

    Authors: David C Hoaglin, Anna Filonenko, Mark E Glickman, Radek Wasiak and Risha Gidwani
    Citation: European Journal of Medical Research 2013 18:17
  43. Recent studies haveshown that ginsenoside Rg1, extracted from the dry roots of Panax notoginseng as a traditional Asian medicine, plays an anti-fibrosis role in myocardial remodeling. However, the mechanism still...

    Authors: Chang-yi Li, Wang Deng, Xiu-qing Liao, Jia Deng, Yu-kun Zhang and Dao-xin Wang
    Citation: European Journal of Medical Research 2013 18:16
  44. Osteoporosis affects 200 million people worldwide and places an enormous economic burden on society. We aim to identify the feature genes that are related to osteoprotegerin in osteoporosis and to perform func...

    Authors: Xiaoming Wu, Shuzhang Guo, Guanghao Shen, Xing Ma, Chi Tang, Kangning Xie, Juan Liu, Wei Guo, Yili Yan and Erping Luo
    Citation: European Journal of Medical Research 2013 18:15
  45. Streptococcus pneumoniae (SP) is the major cause of childhood mortality worldwide, we need to understand virulence genes of SP so can better target the treatment.

    Authors: Da-kang Hu, Dong-guo Wang, Yang Liu, Chi-bo Liu, Lian-hua Yu, Ying Qu, Xin-hua Luo, Jin-hong Yang, Jian Yu, Jin Zhang and Xiang-yang Li
    Citation: European Journal of Medical Research 2013 18:14
  46. The aim of the study was to test for human papilloma virus (HPV) infection and human telomerase RNA component (hTERC) gene amplification in tissues derived from esophageal cancer, in esophagus displaying atypi...

    Authors: Yu-Feng Wang, Xin-Shuai Wang, She-Gan Gao, Qiang Chen, Yan-Tong Yang, Zhong-Yue Xiao, Xiu-Qing Peng, Xiu-Feng Hu, Qia-Yin Wang and Xiao-Shan Feng
    Citation: European Journal of Medical Research 2013 18:11

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