Sarin KY, Artandi SE. Aging, graying and loss of melanocyte stem cells. Stem Cell Rev. 2007;3(3):212–7.
Article
CAS
PubMed
Google Scholar
Redondo P, del Olmo J, García-Guzman M, Guembe L, Prósper F. Repigmentation of vitiligo by transplantation of autologous melanocyte cells cultured on amniotic membrane. Br J Dermatol. 2008y;158(5):1168–71.
Article
CAS
PubMed
Google Scholar
Rosen CJ, Holick MF, Millard PS. Premature graying of hair is a risk marker for osteopenia. J Clin Endocrinol Metab. 1994;79(3):854–7.
CAS
PubMed
Google Scholar
Penzi LR, Manatis-Lornell A, Saavedra A, Fisher D, Senna MM. Hair repigmentation associated with the use of brentuximab. JAAD Case Rep. 2017;3(6):563–5.
Article
PubMed
PubMed Central
Google Scholar
Rongioletti F, Mugheddu C, Murgia S. Repigmentation and new growth of hairs after anti–interleukin-17 therapy with secukinumab for psoriasis. JAAD Case Rep. 2018;4(5):486–8.
Article
PubMed
PubMed Central
Google Scholar
Rivera N, Boada A, Bielsa MI, Fernández-Figueras MT, Carcereny E, Moran MT, et al. Hair repigmentation during immunotherapy treatment with an anti-programmed cell death 1 and anti-programmed cell death ligand 1 agent for lung cancer. JAMA Dermatol. 2017;153(11):1162–5.
Article
PubMed
PubMed Central
Google Scholar
Tintle SJ, Dabade TS, Kalish RA, Rosmarin DM. Repigmentation of hair following adalimumab therapy. Dermatol Online J. 2015. https://doi.org/10.5070/D3216027818.
Article
PubMed
Google Scholar
Nishimura EK, Granter SR, Fisher DE. Mechanisms of hair graying: incomplete melanocyte stem cell maintenance in the niche. Science. 2005;307(5710):720–4.
Article
CAS
PubMed
Google Scholar
Tobin DJ. Aging of the hair follicle pigmentation system. Int J Trichol. 2009;1(2):83–93.
Article
Google Scholar
Arck PC, Overall R, Spatz K, Liezman C, Handjiski B, Klapp BF, et al. Towards a “free radical theory of graying”: melanocyte apoptosis in the aging human hair follicle is an indicator of oxidative stress induced tissue damage. FASEB J Off Publ Fed Am Soc Exp Biol. 2006;20(9):1567–9.
CAS
Google Scholar
Poon W, Vos P, Muresanu D, Vester J, von Wild K, Hömberg V, et al. Cerebrolysin Asian Pacific trial in acute brain injury and neurorecovery: design and methods. J Neurotrauma. 2015;32(8):571–80.
Article
PubMed
Google Scholar
Zhang Y, Chopp M, Gang Zhang Z, Zhang Y, Zhang L, Lu M, et al. Prospective, randomized, blinded, and placebo-controlled study of Cerebrolysin dose-response effects on long-term functional outcomes in a rat model of mild traumatic brain injury. J Neurosurg. 2018;129(5):1295–304.
Article
CAS
PubMed
Google Scholar
Plosker GL, Gauthier S. Cerebrolysin: a review of its use in dementia. Drugs Aging. 2009;26(11):893–915.
Article
CAS
PubMed
Google Scholar
Bornstein NM, Guekht A, Vester J, Heiss WD, Gusev E, Hömberg V, et al. Safety and efficacy of Cerebrolysin in early post-stroke recovery: a meta-analysis of nine randomized clinical trials. Neurol Sci Off J Ital Neurol Soc Ital Soc Clin Neurophysiol. 2018;39(4):629–40.
Google Scholar
Nasiri J, Safavifar F. Effect of cerebrolysin on gross motor function of children with cerebral palsy: a clinical trial. Acta Neurol Belg. 2017;117(2):501–5.
Article
PubMed
Google Scholar
Chen N, Yang M, Guo J, Zhou M, Zhu C, He L. Cerebrolysin for vascular dementia. Cochrane Database Syst Rev. 2013. https://doi.org/10.1002/14651858.CD008900.pub2.
Article
PubMed
PubMed Central
Google Scholar
Park YK, Yi HJ, Choi KS, Lee YJ, Kim DW, Kwon SM. Cerebrolysin for the treatment of aneurysmal subarachnoid hemorrhage in adults: a retrospective chart review. Adv Ther. 2018;35(12):2224–35.
Article
CAS
PubMed
PubMed Central
Google Scholar
Keilhoff G, Lucas B, Pinkernelle J, Steiner M, Fansa H. Effects of cerebrolysin on motor-neuron-like NSC-34 cells. Exp Cell Res. 2014;327(2):234–55.
Article
CAS
PubMed
Google Scholar
Lucas B, Pinkernelle J, Fansa H, Keilhoff G. Effects of cerebrolysin on rat Schwann cells in vitro. Acta Histochem. 2014;116(5):820–30.
Article
CAS
PubMed
Google Scholar
Zhang L, Chopp M, Meier DH, Winter S, Wang L, Szalad A, et al. Sonic hedgehog signaling pathway mediates cerebrolysin-improved neurological function after stroke. Stroke. 2013;44(7):1965–72.
Article
CAS
PubMed
Google Scholar
Vester JC, Buzoianu AD, Florian SI, Hömberg V, Kim SH, Lee TMC, et al. Cerebrolysin after moderate to severe traumatic brain injury: prospective meta-analysis of the CAPTAIN trial series. Neurol Sci Off J Ital Neurol Soc Ital Soc Clin Neurophysiol. 2021. https://doi.org/10.1007/s10072-020-04974-6.
Article
Google Scholar
Samir A, Nasef N, Fathy K, El-Gilany AH, Yahia S. Effect of cerebrolysin on neurodevelopmental outcome of high risk preterm infants: a randomized controlled trial. J Neonatal-Perinatal Med. 2021. https://doi.org/10.3233/NPM-200659.
Article
Google Scholar
Kocaman SA, Çetin M, Durakoğlugil ME, Erdoğan T, Çanga A, Çiçek Y, et al. The degree of premature hair graying as an independent risk marker for coronary artery disease: a predictor of biological age rather than chronological age. Anadolu Kardiyol Derg AKD Anatol J Cardiol. 2012;12(6):457–63.
Google Scholar
Kumar AB, Shamim H, Nagaraju U. Premature graying of hair: review with updates. Int J Trichol. 2018;10(5):198–203.
Article
Google Scholar
Tobin DJ. Human hair pigmentation–biological aspects. Int J Cosmet Sci. 2008;30(4):233–57.
Article
CAS
PubMed
Google Scholar
Mohanty S, Kumar A, Dhawan J, Sharma VK, Gupta S. Depletion of CD200+ hair follicle stem cells in human prematurely gray hair follicles. J Cutan Aesthetic Surg. 2013;6(2):90–2.
Article
Google Scholar
Schallreuter KU, Salem MAEL, Holtz S, Panske A. Basic evidence for epidermal H2O2/ONOO(-)-mediated oxidation/nitration in segmental vitiligo is supported by repigmentation of skin and eyelashes after reduction of epidermal H2O2 with topical NB-UVB-activated pseudocatalase PC-KUS. FASEB J Off Publ Fed Am Soc Exp Biol. 2013;27(8):3113–22.
CAS
Google Scholar
De Mazière AM, Muehlethaler K, van Donselaar E, Salvi S, Davoust J, Cerottini JC, et al. The melanocytic protein Melan-A/MART-1 has a subcellular localization distinct from typical melanosomal proteins. Traffic. 2002;3(9):678–93.
Article
PubMed
Google Scholar
Hoashi T, Watabe H, Muller J, Yamaguchi Y, Vieira WD, Hearing VJ. MART-1 is required for the function of the melanosomal matrix protein PMEL17/GP100 and the maturation of melanosomes. J Biol Chem. 2005;280(14):14006–16.
Article
CAS
PubMed
Google Scholar
Formichi P, Radi E, Battisti C, Di Maio G, Muresanu D, Federico A. Cerebrolysin administration reduces oxidative stress-induced apoptosis in lymphocytes from healthy individuals. J Cell Mol Med. 2012;16(11):2840–3.
Article
CAS
PubMed
PubMed Central
Google Scholar
Ubhi K, Rockenstein E, Vazquez-Roque R, Mante M, Inglis C, Patrick C, et al. Cerebrolysin modulates pronerve growth factor/nerve growth factor ratio and ameliorates the cholinergic deficit in a transgenic model of Alzheimer’s disease. J Neurosci Res. 2013;91(2):167–77.
Article
CAS
PubMed
Google Scholar
Vázquez-Roque RA, Ubhi K, Masliah E, Flores G. Chronic cerebrolysin administration attenuates neuronal abnormalities in the basolateral amygdala induced by neonatal ventral hippocampus lesion in the rat. Synapse. 2014;68(1):31–8.
Article
PubMed
Google Scholar
Fonseca-Pereira D, Arroz-Madeira S, Rodrigues-Campos M, Barbosa IAM, Domingues RG, Bento T, et al. The neurotrophic factor receptor RET drives haematopoietic stem cell survival and function. Nature. 2014;514(7520):98–101.
Article
CAS
PubMed
Google Scholar
Botchkarev VA, Botchkareva NV, Albers KM, Chen LH, Welker P, Paus R. A role for p75 neurotrophin receptor in the control of apoptosis-driven hair follicle regression. FASEB J Off Publ Fed Am Soc Exp Biol. 2000;14(13):1931–42.
CAS
Google Scholar
Powers WJ, Rabinstein AA, Ackerson T, Adeoye OM, Bambakidis NC, Becker K, et al. 2018 Guidelines for the early management of patients with acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2018;49(3):e46-110.
Article
PubMed
Google Scholar
Onose G, Mureşanu DF, Ciurea AV, Daia Chendreanu C, Mihaescu AS, Mardare DC, et al. Neuroprotective and consequent neurorehabilitative clinical outcomes, in patients treated with the pleiotropic drug cerebrolysin. J Med Life. 2009;2(4):350–60.
CAS
PubMed
PubMed Central
Google Scholar
Hartbauer M, Hutter-Paier B, Skofitsch G, Windisch M. Antiapoptotic effects of the peptidergic drug cerebrolysin on primary cultures of embryonic chick cortical neurons. J Neural Transm. 2001;108(4):459–73.
Article
CAS
PubMed
Google Scholar
Zhang C, Chopp M, Cui Y, Wang L, Zhang R, Zhang L, et al. Cerebrolysin enhances neurogenesis in the ischemic brain and improves functional outcome after stroke. J Neurosci Res. 2010;88(15):3275–81.
Article
CAS
PubMed
PubMed Central
Google Scholar
Hutter-Paier B, Steiner E, Windisch M. Cerebrolysin protects isolated cortical neurons from neurodegeneration after brief histotoxic hypoxia. J Neural Transm Suppl. 1998;53:351–61.
Article
CAS
PubMed
Google Scholar
Inomata K, Aoto T, Binh NT, Okamoto N, Tanimura S, Wakayama T, et al. Genotoxic stress abrogates renewal of melanocyte stem cells by triggering their differentiation. Cell. 2009;137(6):1088–99.
Article
CAS
PubMed
Google Scholar
Magnoni S, Stocchetti N, Colombo G, Carlin A, Colombo A, Lipton JM, et al. Alpha-melanocyte-stimulating hormone is decreased in plasma of patients with acute brain injury. J Neurotrauma. 2003;20(3):251–60.
Article
PubMed
Google Scholar
Sharma HS, Muresanu DF, Lafuente JV, Patnaik R, Tian ZR, Ozkizilcik A, et al. Co-administration of TiO2 nanowired mesenchymal stem cells with cerebrolysin potentiates neprilysin level and reduces brain pathology in Alzheimer’s disease. Mol Neurobiol. 2018;55(1):300–11.
Article
CAS
PubMed
Google Scholar
Tobin DJ. The cell biology of human hair follicle pigmentation. Pigment Cell Melanoma Res. 2011;24(1):75–88.
Article
PubMed
Google Scholar